Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet

Supercritical fluid extraction (SFE) using carbon dioxide (CO2) and liquid CO2 using Soxhlet (CO2-Soxhlet) extraction were employed to extract three (3) antidiabetic compounds viz. stigmasterol, quercetin, and avicularin from Mimosa pudica. Various extraction parameters were studied. Extracts were a...

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Main Authors:	Tunna, Tasnuva Sarwar, Sarker, Md. Zaidul Islam, Ghafoor, Kashif, Ferdosh, Sahena, Md Jaffri, Juliana, AL-Juhaımı, Fahad Y.I., Ali, Md Eaqub, Akanda, Md Jahurul Haque, Awal, Md Shihabul, Ahmed, Qamar Uddin, Selamat, Jinap
Format:	Article
Language:	English English English
Published:	http://www.tandfonline.com/loi/lsst20 2018
Subjects:	RS192 Materia Medica-Pharmaceutical Technology
Online Access:	http://irep.iium.edu.my/60532/ http://irep.iium.edu.my/60532/ http://irep.iium.edu.my/60532/ http://irep.iium.edu.my/60532/1/SST-Tunna-Zaidul-2017.pdf http://irep.iium.edu.my/60532/7/60532_Enrichment%2C%20in%20vitro%2C%20and%20quantification_scopus.pdf http://irep.iium.edu.my/60532/13/60532_Enrichment%2C%20in%20vitro%2C%20and%20quantification%20_WoS.pdf

id	iium-60532
recordtype	eprints
spelling	iium-605322018-10-18T01:37:48Z http://irep.iium.edu.my/60532/ Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet Tunna, Tasnuva Sarwar Sarker, Md. Zaidul Islam Ghafoor, Kashif Ferdosh, Sahena Md Jaffri, Juliana AL-Juhaımı, Fahad Y.I. Ali, Md Eaqub Akanda, Md Jahurul Haque Awal, Md Shihabul Ahmed, Qamar Uddin Selamat, Jinap RS192 Materia Medica-Pharmaceutical Technology Supercritical fluid extraction (SFE) using carbon dioxide (CO2) and liquid CO2 using Soxhlet (CO2-Soxhlet) extraction were employed to extract three (3) antidiabetic compounds viz. stigmasterol, quercetin, and avicularin from Mimosa pudica. Various extraction parameters were studied. Extracts were analyzed pharmacologically, qualitatively and quantitatively to ascertain enrichment levels. All three antidiabetic compounds were effectively enriched under optimized conditions of temperature 60°C, pressure 40 MPa, co-solvent ratio 30%, and CO2 flow rate of 5 ml min−1. SFE was found to be the better method for enrichment of the antidiabetic compounds than the CO2-Soxhlet method. Extraction conditions were seen to affect the enrichment of desired compounds. http://www.tandfonline.com/loi/lsst20 2018-01-22 Article PeerReviewed application/pdf en http://irep.iium.edu.my/60532/1/SST-Tunna-Zaidul-2017.pdf application/pdf en http://irep.iium.edu.my/60532/7/60532_Enrichment%2C%20in%20vitro%2C%20and%20quantification_scopus.pdf application/pdf en http://irep.iium.edu.my/60532/13/60532_Enrichment%2C%20in%20vitro%2C%20and%20quantification%20_WoS.pdf Tunna, Tasnuva Sarwar and Sarker, Md. Zaidul Islam and Ghafoor, Kashif and Ferdosh, Sahena and Md Jaffri, Juliana and AL-Juhaımı, Fahad Y.I. and Ali, Md Eaqub and Akanda, Md Jahurul Haque and Awal, Md Shihabul and Ahmed, Qamar Uddin and Selamat, Jinap (2018) Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet. Separation Science and Technology, 53 (2). pp. 243-260. ISSN 0149-6395 E-ISSN 1520-5754 http://www.tandfonline.com/loi/lsst20 10.1080/01496395.2017.1384015
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	RS192 Materia Medica-Pharmaceutical Technology
spellingShingle	RS192 Materia Medica-Pharmaceutical Technology Tunna, Tasnuva Sarwar Sarker, Md. Zaidul Islam Ghafoor, Kashif Ferdosh, Sahena Md Jaffri, Juliana AL-Juhaımı, Fahad Y.I. Ali, Md Eaqub Akanda, Md Jahurul Haque Awal, Md Shihabul Ahmed, Qamar Uddin Selamat, Jinap Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
description	Supercritical fluid extraction (SFE) using carbon dioxide (CO2) and liquid CO2 using Soxhlet (CO2-Soxhlet) extraction were employed to extract three (3) antidiabetic compounds viz. stigmasterol, quercetin, and avicularin from Mimosa pudica. Various extraction parameters were studied. Extracts were analyzed pharmacologically, qualitatively and quantitatively to ascertain enrichment levels. All three antidiabetic compounds were effectively enriched under optimized conditions of temperature 60°C, pressure 40 MPa, co-solvent ratio 30%, and CO2 flow rate of 5 ml min−1. SFE was found to be the better method for enrichment of the antidiabetic compounds than the CO2-Soxhlet method. Extraction conditions were seen to affect the enrichment of desired compounds.
format	Article
author	Tunna, Tasnuva Sarwar Sarker, Md. Zaidul Islam Ghafoor, Kashif Ferdosh, Sahena Md Jaffri, Juliana AL-Juhaımı, Fahad Y.I. Ali, Md Eaqub Akanda, Md Jahurul Haque Awal, Md Shihabul Ahmed, Qamar Uddin Selamat, Jinap
author_facet	Tunna, Tasnuva Sarwar Sarker, Md. Zaidul Islam Ghafoor, Kashif Ferdosh, Sahena Md Jaffri, Juliana AL-Juhaımı, Fahad Y.I. Ali, Md Eaqub Akanda, Md Jahurul Haque Awal, Md Shihabul Ahmed, Qamar Uddin Selamat, Jinap
author_sort	Tunna, Tasnuva Sarwar
title	Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
title_short	Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
title_full	Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
title_fullStr	Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
title_full_unstemmed	Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet
title_sort	enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed mimosa pudica using supercritical co2 and co2-soxhlet
publisher	http://www.tandfonline.com/loi/lsst20
publishDate	2018
url	http://irep.iium.edu.my/60532/ http://irep.iium.edu.my/60532/ http://irep.iium.edu.my/60532/ http://irep.iium.edu.my/60532/1/SST-Tunna-Zaidul-2017.pdf http://irep.iium.edu.my/60532/7/60532_Enrichment%2C%20in%20vitro%2C%20and%20quantification_scopus.pdf http://irep.iium.edu.my/60532/13/60532_Enrichment%2C%20in%20vitro%2C%20and%20quantification%20_WoS.pdf
first_indexed	2023-09-18T21:25:49Z
last_indexed	2023-09-18T21:25:49Z
_version_	1777412184351965184

Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet

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