Screening of aphrodisiac property in sea slug, aplysia dactylomela
Objective: To evaluate the aphrodisiac property of Aplysia dactylomela (A. dactylomelan), locally known as 'dugu-dugu', which is one of the sea slug species. Methods: Two types of extractions were used: aqueous and lipid. Three doses of each A. dactylomelan extract, respectively; 50, 100,...
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Elsevier (Singapore) Pte Ltd
2014
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iium-420932017-09-25T10:22:33Z http://irep.iium.edu.my/42093/ Screening of aphrodisiac property in sea slug, aplysia dactylomela Hashim, Ridzwan Mohd Roslan, Noor Atika Elliyana Zulkipli, Farah Hanis Mohd Daud, Jamaluddin R Medicine (General) Objective: To evaluate the aphrodisiac property of Aplysia dactylomela (A. dactylomelan), locally known as 'dugu-dugu', which is one of the sea slug species. Methods: Two types of extractions were used: aqueous and lipid. Three doses of each A. dactylomelan extract, respectively; 50, 100, 200 mg/kg were administered (i.p.) to male mice for mounting behavior test. Sildenafil citrate or Viagra(R) (5 mg/kg) being positive control while negative control received saline solution. Results: The animals treated with lipid extract at the respective dose exhibited mounting behavior, but the mounting frequency decreased at higher doses (100 and 200 mg/kg). However, all doses of aqueous extract did not show any mounting behavior. Meanwhile, in all doses of lipid extracts administered displayed significant difference 9P<0.05) from the positive control. Despite this, only the lipid extract of 50 mg/kg showed significant difference (P<0.05) with negative control. This signifies that lipid extracts especially in dose 50 mg/kg have a substantial effect of aphrodisiac property. In addition, the presence of steroids was detected in the phytochemical screening of lipid extract. Conclusions: The findings from this study provides preliminary scientific evidence that A. dactylomela could be used as an alternative medication of natural product for promoting sexual activity in men. Elsevier (Singapore) Pte Ltd 2014-09-17 Article PeerReviewed application/pdf en http://irep.iium.edu.my/42093/1/Paper_Dugo_dugoRidzwan_%26_Jamaluddin_2004_1-s2.0-S1995764514602224-main.pdf application/pdf en http://irep.iium.edu.my/42093/4/42093_Screening%20of%20aphrodisiac%20_article.pdf Hashim, Ridzwan and Mohd Roslan, Noor Atika Elliyana and Zulkipli, Farah Hanis and Mohd Daud, Jamaluddin (2014) Screening of aphrodisiac property in sea slug, aplysia dactylomela. Asian Pacific Journal of Tropical Medicine, 7 (1). S150-S154. ISSN 1995-7645 http://www.journals.elsevier.com/asian-pacific-journal-of-tropical-medicine/ 10.1016/S1995-7645(14)60222-4 |
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R Medicine (General) Hashim, Ridzwan Mohd Roslan, Noor Atika Elliyana Zulkipli, Farah Hanis Mohd Daud, Jamaluddin Screening of aphrodisiac property in sea slug, aplysia dactylomela |
description |
Objective: To evaluate the aphrodisiac property of Aplysia dactylomela (A. dactylomelan), locally known as 'dugu-dugu', which is one of the sea slug species.
Methods: Two types of extractions were used: aqueous and lipid. Three doses of each A. dactylomelan extract, respectively; 50, 100, 200 mg/kg were administered (i.p.) to male mice for mounting behavior test. Sildenafil citrate or Viagra(R) (5 mg/kg) being positive control while negative control received saline solution.
Results: The animals treated with lipid extract at the respective dose exhibited mounting behavior, but the mounting frequency decreased at higher doses (100 and 200 mg/kg). However, all doses of aqueous extract did not show any mounting behavior. Meanwhile, in all doses of lipid extracts administered displayed significant difference 9P<0.05) from the positive control. Despite this, only the lipid extract of 50 mg/kg showed significant difference (P<0.05) with negative control. This signifies that lipid extracts especially in dose 50 mg/kg have a substantial effect of aphrodisiac property. In addition, the presence of steroids was detected in the phytochemical screening of lipid extract.
Conclusions: The findings from this study provides preliminary scientific evidence that A. dactylomela could be used as an alternative medication of natural product for promoting sexual activity in men. |
format |
Article |
author |
Hashim, Ridzwan Mohd Roslan, Noor Atika Elliyana Zulkipli, Farah Hanis Mohd Daud, Jamaluddin |
author_facet |
Hashim, Ridzwan Mohd Roslan, Noor Atika Elliyana Zulkipli, Farah Hanis Mohd Daud, Jamaluddin |
author_sort |
Hashim, Ridzwan |
title |
Screening of aphrodisiac property in sea slug, aplysia dactylomela |
title_short |
Screening of aphrodisiac property in sea slug, aplysia dactylomela |
title_full |
Screening of aphrodisiac property in sea slug, aplysia dactylomela |
title_fullStr |
Screening of aphrodisiac property in sea slug, aplysia dactylomela |
title_full_unstemmed |
Screening of aphrodisiac property in sea slug, aplysia dactylomela |
title_sort |
screening of aphrodisiac property in sea slug, aplysia dactylomela |
publisher |
Elsevier (Singapore) Pte Ltd |
publishDate |
2014 |
url |
http://irep.iium.edu.my/42093/ http://irep.iium.edu.my/42093/ http://irep.iium.edu.my/42093/ http://irep.iium.edu.my/42093/1/Paper_Dugo_dugoRidzwan_%26_Jamaluddin_2004_1-s2.0-S1995764514602224-main.pdf http://irep.iium.edu.my/42093/4/42093_Screening%20of%20aphrodisiac%20_article.pdf |
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2023-09-18T21:00:04Z |
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2023-09-18T21:00:04Z |
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1777410563870031872 |