Screening of aphrodisiac property in sea slug, aplysia dactylomela

Objective: To evaluate the aphrodisiac property of Aplysia dactylomela (A. dactylomelan), locally known as 'dugu-dugu', which is one of the sea slug species. Methods: Two types of extractions were used: aqueous and lipid. Three doses of each A. dactylomelan extract, respectively; 50, 100,...

Full description

Bibliographic Details
Main Authors: Hashim, Ridzwan, Mohd Roslan, Noor Atika Elliyana, Zulkipli, Farah Hanis, Mohd Daud, Jamaluddin
Format: Article
Language:English
English
Published: Elsevier (Singapore) Pte Ltd 2014
Subjects:
Online Access:http://irep.iium.edu.my/42093/
http://irep.iium.edu.my/42093/
http://irep.iium.edu.my/42093/
http://irep.iium.edu.my/42093/1/Paper_Dugo_dugoRidzwan_%26_Jamaluddin_2004_1-s2.0-S1995764514602224-main.pdf
http://irep.iium.edu.my/42093/4/42093_Screening%20of%20aphrodisiac%20_article.pdf
id iium-42093
recordtype eprints
spelling iium-420932017-09-25T10:22:33Z http://irep.iium.edu.my/42093/ Screening of aphrodisiac property in sea slug, aplysia dactylomela Hashim, Ridzwan Mohd Roslan, Noor Atika Elliyana Zulkipli, Farah Hanis Mohd Daud, Jamaluddin R Medicine (General) Objective: To evaluate the aphrodisiac property of Aplysia dactylomela (A. dactylomelan), locally known as 'dugu-dugu', which is one of the sea slug species. Methods: Two types of extractions were used: aqueous and lipid. Three doses of each A. dactylomelan extract, respectively; 50, 100, 200 mg/kg were administered (i.p.) to male mice for mounting behavior test. Sildenafil citrate or Viagra(R) (5 mg/kg) being positive control while negative control received saline solution. Results: The animals treated with lipid extract at the respective dose exhibited mounting behavior, but the mounting frequency decreased at higher doses (100 and 200 mg/kg). However, all doses of aqueous extract did not show any mounting behavior. Meanwhile, in all doses of lipid extracts administered displayed significant difference 9P<0.05) from the positive control. Despite this, only the lipid extract of 50 mg/kg showed significant difference (P<0.05) with negative control. This signifies that lipid extracts especially in dose 50 mg/kg have a substantial effect of aphrodisiac property. In addition, the presence of steroids was detected in the phytochemical screening of lipid extract. Conclusions: The findings from this study provides preliminary scientific evidence that A. dactylomela could be used as an alternative medication of natural product for promoting sexual activity in men. Elsevier (Singapore) Pte Ltd 2014-09-17 Article PeerReviewed application/pdf en http://irep.iium.edu.my/42093/1/Paper_Dugo_dugoRidzwan_%26_Jamaluddin_2004_1-s2.0-S1995764514602224-main.pdf application/pdf en http://irep.iium.edu.my/42093/4/42093_Screening%20of%20aphrodisiac%20_article.pdf Hashim, Ridzwan and Mohd Roslan, Noor Atika Elliyana and Zulkipli, Farah Hanis and Mohd Daud, Jamaluddin (2014) Screening of aphrodisiac property in sea slug, aplysia dactylomela. Asian Pacific Journal of Tropical Medicine, 7 (1). S150-S154. ISSN 1995-7645 http://www.journals.elsevier.com/asian-pacific-journal-of-tropical-medicine/ 10.1016/S1995-7645(14)60222-4
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
topic R Medicine (General)
spellingShingle R Medicine (General)
Hashim, Ridzwan
Mohd Roslan, Noor Atika Elliyana
Zulkipli, Farah Hanis
Mohd Daud, Jamaluddin
Screening of aphrodisiac property in sea slug, aplysia dactylomela
description Objective: To evaluate the aphrodisiac property of Aplysia dactylomela (A. dactylomelan), locally known as 'dugu-dugu', which is one of the sea slug species. Methods: Two types of extractions were used: aqueous and lipid. Three doses of each A. dactylomelan extract, respectively; 50, 100, 200 mg/kg were administered (i.p.) to male mice for mounting behavior test. Sildenafil citrate or Viagra(R) (5 mg/kg) being positive control while negative control received saline solution. Results: The animals treated with lipid extract at the respective dose exhibited mounting behavior, but the mounting frequency decreased at higher doses (100 and 200 mg/kg). However, all doses of aqueous extract did not show any mounting behavior. Meanwhile, in all doses of lipid extracts administered displayed significant difference 9P<0.05) from the positive control. Despite this, only the lipid extract of 50 mg/kg showed significant difference (P<0.05) with negative control. This signifies that lipid extracts especially in dose 50 mg/kg have a substantial effect of aphrodisiac property. In addition, the presence of steroids was detected in the phytochemical screening of lipid extract. Conclusions: The findings from this study provides preliminary scientific evidence that A. dactylomela could be used as an alternative medication of natural product for promoting sexual activity in men.
format Article
author Hashim, Ridzwan
Mohd Roslan, Noor Atika Elliyana
Zulkipli, Farah Hanis
Mohd Daud, Jamaluddin
author_facet Hashim, Ridzwan
Mohd Roslan, Noor Atika Elliyana
Zulkipli, Farah Hanis
Mohd Daud, Jamaluddin
author_sort Hashim, Ridzwan
title Screening of aphrodisiac property in sea slug, aplysia dactylomela
title_short Screening of aphrodisiac property in sea slug, aplysia dactylomela
title_full Screening of aphrodisiac property in sea slug, aplysia dactylomela
title_fullStr Screening of aphrodisiac property in sea slug, aplysia dactylomela
title_full_unstemmed Screening of aphrodisiac property in sea slug, aplysia dactylomela
title_sort screening of aphrodisiac property in sea slug, aplysia dactylomela
publisher Elsevier (Singapore) Pte Ltd
publishDate 2014
url http://irep.iium.edu.my/42093/
http://irep.iium.edu.my/42093/
http://irep.iium.edu.my/42093/
http://irep.iium.edu.my/42093/1/Paper_Dugo_dugoRidzwan_%26_Jamaluddin_2004_1-s2.0-S1995764514602224-main.pdf
http://irep.iium.edu.my/42093/4/42093_Screening%20of%20aphrodisiac%20_article.pdf
first_indexed 2023-09-18T21:00:04Z
last_indexed 2023-09-18T21:00:04Z
_version_ 1777410563870031872