Screening of aphrodisiac property in sea slug, aplysia dactylomela
Objective: To evaluate the aphrodisiac property of Aplysia dactylomela (A. dactylomelan), locally known as 'dugu-dugu', which is one of the sea slug species. Methods: Two types of extractions were used: aqueous and lipid. Three doses of each A. dactylomelan extract, respectively; 50, 100,...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
Elsevier (Singapore) Pte Ltd
2014
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/42093/ http://irep.iium.edu.my/42093/ http://irep.iium.edu.my/42093/ http://irep.iium.edu.my/42093/1/Paper_Dugo_dugoRidzwan_%26_Jamaluddin_2004_1-s2.0-S1995764514602224-main.pdf http://irep.iium.edu.my/42093/4/42093_Screening%20of%20aphrodisiac%20_article.pdf |
| Summary: | Objective: To evaluate the aphrodisiac property of Aplysia dactylomela (A. dactylomelan), locally known as 'dugu-dugu', which is one of the sea slug species.
Methods: Two types of extractions were used: aqueous and lipid. Three doses of each A. dactylomelan extract, respectively; 50, 100, 200 mg/kg were administered (i.p.) to male mice for mounting behavior test. Sildenafil citrate or Viagra(R) (5 mg/kg) being positive control while negative control received saline solution.
Results: The animals treated with lipid extract at the respective dose exhibited mounting behavior, but the mounting frequency decreased at higher doses (100 and 200 mg/kg). However, all doses of aqueous extract did not show any mounting behavior. Meanwhile, in all doses of lipid extracts administered displayed significant difference 9P<0.05) from the positive control. Despite this, only the lipid extract of 50 mg/kg showed significant difference (P<0.05) with negative control. This signifies that lipid extracts especially in dose 50 mg/kg have a substantial effect of aphrodisiac property. In addition, the presence of steroids was detected in the phytochemical screening of lipid extract.
Conclusions: The findings from this study provides preliminary scientific evidence that A. dactylomela could be used as an alternative medication of natural product for promoting sexual activity in men. |
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