Design, Synthesis and Docking Studies of Flavokawain B Type Chalcones and Their Cytotoxic Effects on MCF-7 and MDA-MB-231 Cell Lines
Flavokawain B (1) is a natural chalcone extracted from the roots of Piper methysticum, and has been proven to be a potential cytotoxic compound. Using the partial structure of flavokawain B (FKB), about 23 analogs have been synthesized. Among them, compounds 8, 13 and 23 were found in new FKB deriva...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI - Open Access Publishing
2018
|
| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/20646/ http://umpir.ump.edu.my/id/eprint/20646/ http://umpir.ump.edu.my/id/eprint/20646/ http://umpir.ump.edu.my/id/eprint/20646/7/Design%2C%20Synthesis%20and%20Docking%20Studies%20of%20Flavokawain%20B%20Type-fist-2018.pdf |