Divalent cations (Mg2+, Ca2+) protect bacterial outer membrane damage by polymyxin B
Polymyxin B interacts with divalent cations by displacing cations from their binding sites in the lipopolysaccharide (LPS) molecules. It leads to the disorganization of the outer membrane component of the Gram negative bacteria, which releases LPS component from bacterial surface causing severe memb...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Universiti Kebangsaan Malaysia
2013
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| Online Access: | http://journalarticle.ukm.my/5972/ http://journalarticle.ukm.my/5972/ http://journalarticle.ukm.my/5972/1/05%2520Ahmad%2520Zorin.pdf |