Identifying analogues of 2-deoxyglucose, alpha-d-glucose and beta-d-glucose-6-phosphate as potential inhibitors of human hexokinase ii for the development of anti-dengue therapeutics
The human hexokinase isoform II (HKII) is one of the important enzymes for dengue virus (DENV) replication and thus has been suggested as a potential therapeutic target for DENV drug development. In this work, compounds were identified using Ultrafast Shape Recognition with CREDO Atom Types (USRCAT)...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English English English |
| Published: |
Universiti Putra Malaysia Press
2019
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/79647/ http://irep.iium.edu.my/79647/ http://irep.iium.edu.my/79647/1/79647_Identifying%20Analogues%20Of%202-Deoxyglucose.pdf http://irep.iium.edu.my/79647/2/79647_Identifying%20Analogues%20Of%202-Deoxyglucose_SCOPUS.pdf http://irep.iium.edu.my/79647/3/79647_Identifying%20Analogues%20Of%202-Deoxyglucose_WOS.pdf |