Identifying analogues of 2-deoxyglucose, alpha-d-glucose and beta-d-glucose-6-phosphate as potential inhibitors of human hexokinase ii for the development of anti-dengue therapeutics

The human hexokinase isoform II (HKII) is one of the important enzymes for dengue virus (DENV) replication and thus has been suggested as a potential therapeutic target for DENV drug development. In this work, compounds were identified using Ultrafast Shape Recognition with CREDO Atom Types (USRCAT)...

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Bibliographic Details
Main Authors: Tanbin, Suriyea, Ogu Salim, Nurhainis, Ahmad Fuad, Fazia Adyani
Format: Article
Language:English
English
English
Published: Universiti Putra Malaysia Press 2019
Subjects:
Online Access:http://irep.iium.edu.my/79647/
http://irep.iium.edu.my/79647/
http://irep.iium.edu.my/79647/1/79647_Identifying%20Analogues%20Of%202-Deoxyglucose.pdf
http://irep.iium.edu.my/79647/2/79647_Identifying%20Analogues%20Of%202-Deoxyglucose_SCOPUS.pdf
http://irep.iium.edu.my/79647/3/79647_Identifying%20Analogues%20Of%202-Deoxyglucose_WOS.pdf