Determination of fracture risk on patient-specific model of femur with osteogenesis imperfecta
Osteogenesis Imperfecta (OI) is a group of genetic disorder that affects the bones. It causes bone to break easily. For severe case, it can lead the patient to death. However, doctors still have no quantitative method to predict fractures. Therefore, this study aims to investigate the fracture ri...
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IOP Publishing
2019
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iium-796072020-03-18T01:20:26Z http://irep.iium.edu.my/79607/ Determination of fracture risk on patient-specific model of femur with osteogenesis imperfecta Ahmad, Siti Fatima Zahra’ Mat Som, Mohd Hanafi Basaruddin, Khairul Salleh Daud, Ruslizam Awang, Mohd Shukrimi RD701 Orthopedics T Technology (General) Osteogenesis Imperfecta (OI) is a group of genetic disorder that affects the bones. It causes bone to break easily. For severe case, it can lead the patient to death. However, doctors still have no quantitative method to predict fractures. Therefore, this study aims to investigate the fracture risk for OI femoral bone under load of activities in daily living and various loading direction. A finite element model reconstructed from radiography CT images was developed. The variations of daily activities were subjected to the femoral model. In standing and walking configuration, the model of OI has the ability to perform without having any fracture. However, during jumping, both configurations cause the OI femoral fractured. We can conclude that when the OI patients more active in their daily life, the higher chances for fracture to occur. The risk of fracture increases with increasing the intensity of the activity. Thus, early prediction of fracture risk could help prevent or treating fracture for OI patients. IOP Publishing 2019-11-22 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/79607/1/79607%20Determination%20of%20Fracture%20Risk%20on%20Patient-specific.pdf application/pdf en http://irep.iium.edu.my/79607/2/79607%20Determination%20of%20Fracture%20Risk%20on%20Patient-specific%20SCOPUS.pdf Ahmad, Siti Fatima Zahra’ and Mat Som, Mohd Hanafi and Basaruddin, Khairul Salleh and Daud, Ruslizam and Awang, Mohd Shukrimi (2019) Determination of fracture risk on patient-specific model of femur with osteogenesis imperfecta. In: International Conference on Biomedical Engineering, 26th–27th August 2019, Penang Island. https://iopscience.iop.org/article/10.1088/1742-6596/1372/1/012042/pdf 10.1088/1742-6596/1372/1/012042 |
| repository_type |
Digital Repository |
| institution_category |
Local University |
| institution |
International Islamic University Malaysia |
| building |
IIUM Repository |
| collection |
Online Access |
| language |
English English |
| topic |
RD701 Orthopedics T Technology (General) |
| spellingShingle |
RD701 Orthopedics T Technology (General) Ahmad, Siti Fatima Zahra’ Mat Som, Mohd Hanafi Basaruddin, Khairul Salleh Daud, Ruslizam Awang, Mohd Shukrimi Determination of fracture risk on patient-specific model of femur with osteogenesis imperfecta |
| description |
Osteogenesis Imperfecta (OI) is a group of genetic disorder that affects the bones. It
causes bone to break easily. For severe case, it can lead the patient to death. However, doctors
still have no quantitative method to predict fractures. Therefore, this study aims to investigate
the fracture risk for OI femoral bone under load of activities in daily living and various loading
direction. A finite element model reconstructed from radiography CT images was developed.
The variations of daily activities were subjected to the femoral model. In standing and walking
configuration, the model of OI has the ability to perform without having any fracture.
However, during jumping, both configurations cause the OI femoral fractured. We can
conclude that when the OI patients more active in their daily life, the higher chances for
fracture to occur. The risk of fracture increases with increasing the intensity of the activity.
Thus, early prediction of fracture risk could help prevent or treating fracture for OI patients. |
| format |
Conference or Workshop Item |
| author |
Ahmad, Siti Fatima Zahra’ Mat Som, Mohd Hanafi Basaruddin, Khairul Salleh Daud, Ruslizam Awang, Mohd Shukrimi |
| author_facet |
Ahmad, Siti Fatima Zahra’ Mat Som, Mohd Hanafi Basaruddin, Khairul Salleh Daud, Ruslizam Awang, Mohd Shukrimi |
| author_sort |
Ahmad, Siti Fatima Zahra’ |
| title |
Determination of fracture risk on patient-specific model of femur with osteogenesis imperfecta |
| title_short |
Determination of fracture risk on patient-specific model of femur with osteogenesis imperfecta |
| title_full |
Determination of fracture risk on patient-specific model of femur with osteogenesis imperfecta |
| title_fullStr |
Determination of fracture risk on patient-specific model of femur with osteogenesis imperfecta |
| title_full_unstemmed |
Determination of fracture risk on patient-specific model of femur with osteogenesis imperfecta |
| title_sort |
determination of fracture risk on patient-specific model of femur with osteogenesis imperfecta |
| publisher |
IOP Publishing |
| publishDate |
2019 |
| url |
http://irep.iium.edu.my/79607/ http://irep.iium.edu.my/79607/ http://irep.iium.edu.my/79607/ http://irep.iium.edu.my/79607/1/79607%20Determination%20of%20Fracture%20Risk%20on%20Patient-specific.pdf http://irep.iium.edu.my/79607/2/79607%20Determination%20of%20Fracture%20Risk%20on%20Patient-specific%20SCOPUS.pdf |
| first_indexed |
2023-09-18T21:51:36Z |
| last_indexed |
2023-09-18T21:51:36Z |
| _version_ |
1777413805799636992 |