Clinical assessment and morphological changes of minor salivary glands in patients with secondary Sjogren’s Syndrome

Aim: To study the labial salivary gland biopsy fi ndings and to assess the clinical condition of the patients with secondary Sjogren’s syndrome patients. Material and methods: Fifty-six patients were involved in this study,full history was taken and complete clinical examination was done for the...

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Main Authors:	Mustafa, Naziyah Shaban, Mustafa Al-Ahmad, Basma Ezzat, Kashmoola, Muhannad Ali
Format:	Conference or Workshop Item
Language:	English English
Published:	2018
Subjects:	RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
Online Access:	http://irep.iium.edu.my/75020/ http://irep.iium.edu.my/75020/ http://irep.iium.edu.my/75020/4/75020%20abstract.pdf http://irep.iium.edu.my/75020/3/75020%20Clinical%20assessment%20and%20morphological%20changes.pdf

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recordtype	eprints
spelling	iium-750202019-11-05T07:24:19Z http://irep.iium.edu.my/75020/ Clinical assessment and morphological changes of minor salivary glands in patients with secondary Sjogren’s Syndrome Mustafa, Naziyah Shaban Mustafa Al-Ahmad, Basma Ezzat Kashmoola, Muhannad Ali RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works Aim: To study the labial salivary gland biopsy fi ndings and to assess the clinical condition of the patients with secondary Sjogren’s syndrome patients. Material and methods: Fifty-six patients were involved in this study,full history was taken and complete clinical examination was done for the period of 15 months duration. Schirmer’s tear test, salivary fl ow rate were done for all patients. Labial salivary gland biopsy was performed and sent for histopathological study. Results: Schirmer’s tear test was positive with signifi cant reduction in the tear fl ow (P ≤ 0.01), in all patients . A signifi cant reduction in the salivary fl ow rate (p<0.01) in all patients .Clinical assessment showed parotid gland enlargement in 8 patients. Intraoral examination revealed a candidal infection in four patients. The histopathologic study for labial salivary gland biopsy showed a chronic infl ammatory process with lymphocytic infi ltration, acinar atrophy and proliferation of the ductal epithelium which obliterate the duct lumen. Conclusion: Patients with secondary Sjogren’s syndrome proved by labial salivary gland biopsy had a signifi cantly greater frequency to parotid gland enlargement and susceptibility to fungal infection. 2018 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/75020/4/75020%20abstract.pdf application/pdf en http://irep.iium.edu.my/75020/3/75020%20Clinical%20assessment%20and%20morphological%20changes.pdf Mustafa, Naziyah Shaban and Mustafa Al-Ahmad, Basma Ezzat and Kashmoola, Muhannad Ali (2018) Clinical assessment and morphological changes of minor salivary glands in patients with secondary Sjogren’s Syndrome. In: International Congress of Dental and Oral Infections, 7th-9th September 2018, Sakarya, Turkey. (Unpublished) http://doinf.sakarya.edu.tr/sites/doinf.sakarya.edu.tr/file/Doinf_2018.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works
spellingShingle	RK318 Oral and Dental Medicine. Pathology. Diseases-Therapeutics-General Works Mustafa, Naziyah Shaban Mustafa Al-Ahmad, Basma Ezzat Kashmoola, Muhannad Ali Clinical assessment and morphological changes of minor salivary glands in patients with secondary Sjogren’s Syndrome
description	Aim: To study the labial salivary gland biopsy fi ndings and to assess the clinical condition of the patients with secondary Sjogren’s syndrome patients. Material and methods: Fifty-six patients were involved in this study,full history was taken and complete clinical examination was done for the period of 15 months duration. Schirmer’s tear test, salivary fl ow rate were done for all patients. Labial salivary gland biopsy was performed and sent for histopathological study. Results: Schirmer’s tear test was positive with signifi cant reduction in the tear fl ow (P ≤ 0.01), in all patients . A signifi cant reduction in the salivary fl ow rate (p<0.01) in all patients .Clinical assessment showed parotid gland enlargement in 8 patients. Intraoral examination revealed a candidal infection in four patients. The histopathologic study for labial salivary gland biopsy showed a chronic infl ammatory process with lymphocytic infi ltration, acinar atrophy and proliferation of the ductal epithelium which obliterate the duct lumen. Conclusion: Patients with secondary Sjogren’s syndrome proved by labial salivary gland biopsy had a signifi cantly greater frequency to parotid gland enlargement and susceptibility to fungal infection.
format	Conference or Workshop Item
author	Mustafa, Naziyah Shaban Mustafa Al-Ahmad, Basma Ezzat Kashmoola, Muhannad Ali
author_facet	Mustafa, Naziyah Shaban Mustafa Al-Ahmad, Basma Ezzat Kashmoola, Muhannad Ali
author_sort	Mustafa, Naziyah Shaban
title	Clinical assessment and morphological changes of minor salivary glands in patients with secondary Sjogren’s Syndrome
title_short	Clinical assessment and morphological changes of minor salivary glands in patients with secondary Sjogren’s Syndrome
title_full	Clinical assessment and morphological changes of minor salivary glands in patients with secondary Sjogren’s Syndrome
title_fullStr	Clinical assessment and morphological changes of minor salivary glands in patients with secondary Sjogren’s Syndrome
title_full_unstemmed	Clinical assessment and morphological changes of minor salivary glands in patients with secondary Sjogren’s Syndrome
title_sort	clinical assessment and morphological changes of minor salivary glands in patients with secondary sjogren’s syndrome
publishDate	2018
url	http://irep.iium.edu.my/75020/ http://irep.iium.edu.my/75020/ http://irep.iium.edu.my/75020/4/75020%20abstract.pdf http://irep.iium.edu.my/75020/3/75020%20Clinical%20assessment%20and%20morphological%20changes.pdf
first_indexed	2023-09-18T21:46:10Z
last_indexed	2023-09-18T21:46:10Z
_version_	1777413464491294720

Clinical assessment and morphological changes of minor salivary glands in patients with secondary Sjogren’s Syndrome

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