LTBP-2 has a single high-affinity binding site for FGF-2 and blocks FGF-2-induced cell proliferation.
Latent transforming growth factor-beta-1 binding protein-2 (LTBP-2) belongs to the fibrillin-LTBP superfamily of extracellular matrix proteins. LTBPs and fibrillins are involved in the sequestration and storage of latent growth factors, particularly transforming growth factor β (TGF-β), in tissues....
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
Public Library of Science
2015
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/62193/ http://irep.iium.edu.my/62193/ http://irep.iium.edu.my/62193/ http://irep.iium.edu.my/62193/1/LTBP-2%20FGF-2%20paper%20-%20PLOS%20One.pdf http://irep.iium.edu.my/62193/7/62193_LTBP-2%20has%20a%20single%20high-affinity%20binding_scopus.pdf |