Microencapsulation of fish oil using supercritical antisolvent process

In order to improve the encapsulation process, a newly supercritical antisolvent process was developed to encapsulate fish oil using hydroxypropyl methyl cellulose as a polymer. Three factors, namely, temperature, pressure, and feed emulsion rate were optimized using response surface methodology. Th...

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Main Authors:	Karim, Fahim Tamzeedul, Ghafoor, Kashif, Ferdosh, Sahena, Al-Juhaımı,, Fahad Y.I., Ali, Md Eaqub, Yunus, Kamaruzzaman, Hamed, Mir Hoseini, Islam., Ashraful M.A, Asif, Muhammad Kamran, Sarker, Md Zaidul Islam
Format:	Article
Language:	English English
Published:	Elsevier 2017
Subjects:	Q Science (General)
Online Access:	http://irep.iium.edu.my/61760/ http://irep.iium.edu.my/61760/ http://irep.iium.edu.my/61760/ http://irep.iium.edu.my/61760/1/JFDA-Fahim-Zaidul-2017.pdf http://irep.iium.edu.my/61760/7/61760-Microencapsulation%20of%20fish%20oil%20using%20supercritical%20antisolvent%20process-SCOPUS.pdf

id	iium-61760
recordtype	eprints
spelling	iium-617602018-02-01T08:49:07Z http://irep.iium.edu.my/61760/ Microencapsulation of fish oil using supercritical antisolvent process Karim, Fahim Tamzeedul Ghafoor, Kashif Ferdosh, Sahena Al-Juhaımı,, Fahad Y.I. Ali, Md Eaqub Yunus, Kamaruzzaman Hamed, Mir Hoseini Islam., Ashraful M.A Asif, Muhammad Kamran Sarker, Md Zaidul Islam Q Science (General) In order to improve the encapsulation process, a newly supercritical antisolvent process was developed to encapsulate fish oil using hydroxypropyl methyl cellulose as a polymer. Three factors, namely, temperature, pressure, and feed emulsion rate were optimized using response surface methodology. The suitability of the model for predicting the opti-mum response value was evaluated at the conditions of temperature at 60 C, pressure at 150 bar, and feed rate at 1.36 mL/min. At the optimum conditions, particle size of 58.35 mm was obtained. The surface morphology of the micronized fish oil was also evaluated using field emission scanning electron microscopy where it showed that particles formed spherical structures with no internal voids. Moreover, in vitro release of oil showed that there are significant differences of release percentage of oil between the formulations and the results proved that there was a significant decrease in the in vitro release of oil from the powder when the polymer concentration was high. Elsevier 2017-07 Article PeerReviewed application/pdf en http://irep.iium.edu.my/61760/1/JFDA-Fahim-Zaidul-2017.pdf application/pdf en http://irep.iium.edu.my/61760/7/61760-Microencapsulation%20of%20fish%20oil%20using%20supercritical%20antisolvent%20process-SCOPUS.pdf Karim, Fahim Tamzeedul and Ghafoor, Kashif and Ferdosh, Sahena and Al-Juhaımı,, Fahad Y.I. and Ali, Md Eaqub and Yunus, Kamaruzzaman and Hamed, Mir Hoseini and Islam., Ashraful M.A and Asif, Muhammad Kamran and Sarker, Md Zaidul Islam (2017) Microencapsulation of fish oil using supercritical antisolvent process. Journal of Food and Drug Analysis, 25 (3). pp. 654-666. https://ac.els-cdn.com/S1021949817300297/1-s2.0-S1021949817300297-main.pdf?_tid=54f1f5a0-0723-11e8-bae8-00000aacb360&acdnat=1517471076_3c33f12d87750eeadd1b8b7346288e4b 10.1016/j.jfda.2016.11.017
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	Q Science (General)
spellingShingle	Q Science (General) Karim, Fahim Tamzeedul Ghafoor, Kashif Ferdosh, Sahena Al-Juhaımı,, Fahad Y.I. Ali, Md Eaqub Yunus, Kamaruzzaman Hamed, Mir Hoseini Islam., Ashraful M.A Asif, Muhammad Kamran Sarker, Md Zaidul Islam Microencapsulation of fish oil using supercritical antisolvent process
description	In order to improve the encapsulation process, a newly supercritical antisolvent process was developed to encapsulate fish oil using hydroxypropyl methyl cellulose as a polymer. Three factors, namely, temperature, pressure, and feed emulsion rate were optimized using response surface methodology. The suitability of the model for predicting the opti-mum response value was evaluated at the conditions of temperature at 60 C, pressure at 150 bar, and feed rate at 1.36 mL/min. At the optimum conditions, particle size of 58.35 mm was obtained. The surface morphology of the micronized fish oil was also evaluated using field emission scanning electron microscopy where it showed that particles formed spherical structures with no internal voids. Moreover, in vitro release of oil showed that there are significant differences of release percentage of oil between the formulations and the results proved that there was a significant decrease in the in vitro release of oil from the powder when the polymer concentration was high.
format	Article
author	Karim, Fahim Tamzeedul Ghafoor, Kashif Ferdosh, Sahena Al-Juhaımı,, Fahad Y.I. Ali, Md Eaqub Yunus, Kamaruzzaman Hamed, Mir Hoseini Islam., Ashraful M.A Asif, Muhammad Kamran Sarker, Md Zaidul Islam
author_facet	Karim, Fahim Tamzeedul Ghafoor, Kashif Ferdosh, Sahena Al-Juhaımı,, Fahad Y.I. Ali, Md Eaqub Yunus, Kamaruzzaman Hamed, Mir Hoseini Islam., Ashraful M.A Asif, Muhammad Kamran Sarker, Md Zaidul Islam
author_sort	Karim, Fahim Tamzeedul
title	Microencapsulation of fish oil using supercritical antisolvent process
title_short	Microencapsulation of fish oil using supercritical antisolvent process
title_full	Microencapsulation of fish oil using supercritical antisolvent process
title_fullStr	Microencapsulation of fish oil using supercritical antisolvent process
title_full_unstemmed	Microencapsulation of fish oil using supercritical antisolvent process
title_sort	microencapsulation of fish oil using supercritical antisolvent process
publisher	Elsevier
publishDate	2017
url	http://irep.iium.edu.my/61760/ http://irep.iium.edu.my/61760/ http://irep.iium.edu.my/61760/ http://irep.iium.edu.my/61760/1/JFDA-Fahim-Zaidul-2017.pdf http://irep.iium.edu.my/61760/7/61760-Microencapsulation%20of%20fish%20oil%20using%20supercritical%20antisolvent%20process-SCOPUS.pdf
first_indexed	2023-09-18T21:27:35Z
last_indexed	2023-09-18T21:27:35Z
_version_	1777412295084736512

Microencapsulation of fish oil using supercritical antisolvent process

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