A map of human PRDM9 binding provides evidence for novel behaviors of PRDM9 and other zinc-finger proteins in meiosis
PRDM9 binding localizes almost all meiotic recombination sites in humans and mice. However, most PRDM9-bound loci do not become recombination hotspots. To explore factors that affect binding and subsequent recombination outcomes, we mapped human PRDM9 binding sites in a transfected human cell line a...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
eLife Sciences Publications
2017
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/59029/ http://irep.iium.edu.my/59029/ http://irep.iium.edu.my/59029/ http://irep.iium.edu.my/59029/13/59029-A%20map%20of%20human%20PRDM9%20binding.pdf http://irep.iium.edu.my/59029/7/59029-A%20map%20of%20human%20PRDM9%20binding_scopus.pdf |