Characterization of antioxidant activity of Momordica Charantia fruit by infrared-based fingerprinting

Momordica charantia is widely consumed edible fruit. The food and pharmaceutical industries use it as a natural antioxidant. However, the quality control of M. charantia-based medicinal products is questionable due to the complexity of metabolites in this fruit. Hence, this study has developed a...

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Main Authors:	Khatib, Alfi, Perumal, Vikneswari, Ahmed, Qamar Uddin, Uzir, Bisha Fathamah, Abas, Faridah, Murugesu, Suganya
Format:	Article
Language:	English English
Published:	Taylor & Francis Group 2017
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/58997/ http://irep.iium.edu.my/58997/ http://irep.iium.edu.my/58997/ http://irep.iium.edu.my/58997/8/58997-Characterization%20of%20Antioxidant%20Activity.pdf http://irep.iium.edu.my/58997/7/58997-Characterization%20of%20Antioxidant%20Activity-SCOPUS.pdf

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recordtype	eprints
spelling	iium-589972017-11-08T01:16:42Z http://irep.iium.edu.my/58997/ Characterization of antioxidant activity of Momordica Charantia fruit by infrared-based fingerprinting Khatib, Alfi Perumal, Vikneswari Ahmed, Qamar Uddin Uzir, Bisha Fathamah Abas, Faridah Murugesu, Suganya QD Chemistry Momordica charantia is widely consumed edible fruit. The food and pharmaceutical industries use it as a natural antioxidant. However, the quality control of M. charantia-based medicinal products is questionable due to the complexity of metabolites in this fruit. Hence, this study has developed a statistical model in predicting the antioxidant value through the 2, 2-diphenyl-1 picrylhydrazyl radical scavenging activity and ferric reducing antioxidant power based on infrared spectroscopy with attenuated total reflectance. This technique was reliably used for quality control. Six ethanol extracts (0, 20, 40, 60, 80, and 100% in water) of this plant’s fruit were prepared. The radical scavenging and ferric reducing antioxidant power activities were measured and the chemical profiling of the extracts was fingerprinted by infrared spectroscopy between 4,000 and 600 cm−1 at a resolution of 4 cm−1. Statistical analysis was developed by correlating the bioactivity and infrared spectra of each extract using orthogonal partial least square discriminant analysis. The C–N, C=O, C–O, C–H, and OH infrared signals were positively correlated with biological activity. The antioxidant activity of the fruit of M. charantia may be due to the presence of several antioxidants that work synergistically. Taylor & Francis Group 2017-06-19 Article PeerReviewed application/pdf en http://irep.iium.edu.my/58997/8/58997-Characterization%20of%20Antioxidant%20Activity.pdf application/pdf en http://irep.iium.edu.my/58997/7/58997-Characterization%20of%20Antioxidant%20Activity-SCOPUS.pdf Khatib, Alfi and Perumal, Vikneswari and Ahmed, Qamar Uddin and Uzir, Bisha Fathamah and Abas, Faridah and Murugesu, Suganya (2017) Characterization of antioxidant activity of Momordica Charantia fruit by infrared-based fingerprinting. Analytical Letters, 50 (12). pp. 1977-1991. (In Press) http://www.tandfonline.com/doi/abs/10.1080/00032719.2016.1261877 10.1080/00032719.2016.1261877
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	QD Chemistry
spellingShingle	QD Chemistry Khatib, Alfi Perumal, Vikneswari Ahmed, Qamar Uddin Uzir, Bisha Fathamah Abas, Faridah Murugesu, Suganya Characterization of antioxidant activity of Momordica Charantia fruit by infrared-based fingerprinting
description	Momordica charantia is widely consumed edible fruit. The food and pharmaceutical industries use it as a natural antioxidant. However, the quality control of M. charantia-based medicinal products is questionable due to the complexity of metabolites in this fruit. Hence, this study has developed a statistical model in predicting the antioxidant value through the 2, 2-diphenyl-1 picrylhydrazyl radical scavenging activity and ferric reducing antioxidant power based on infrared spectroscopy with attenuated total reflectance. This technique was reliably used for quality control. Six ethanol extracts (0, 20, 40, 60, 80, and 100% in water) of this plant’s fruit were prepared. The radical scavenging and ferric reducing antioxidant power activities were measured and the chemical profiling of the extracts was fingerprinted by infrared spectroscopy between 4,000 and 600 cm−1 at a resolution of 4 cm−1. Statistical analysis was developed by correlating the bioactivity and infrared spectra of each extract using orthogonal partial least square discriminant analysis. The C–N, C=O, C–O, C–H, and OH infrared signals were positively correlated with biological activity. The antioxidant activity of the fruit of M. charantia may be due to the presence of several antioxidants that work synergistically.
format	Article
author	Khatib, Alfi Perumal, Vikneswari Ahmed, Qamar Uddin Uzir, Bisha Fathamah Abas, Faridah Murugesu, Suganya
author_facet	Khatib, Alfi Perumal, Vikneswari Ahmed, Qamar Uddin Uzir, Bisha Fathamah Abas, Faridah Murugesu, Suganya
author_sort	Khatib, Alfi
title	Characterization of antioxidant activity of Momordica Charantia fruit by infrared-based fingerprinting
title_short	Characterization of antioxidant activity of Momordica Charantia fruit by infrared-based fingerprinting
title_full	Characterization of antioxidant activity of Momordica Charantia fruit by infrared-based fingerprinting
title_fullStr	Characterization of antioxidant activity of Momordica Charantia fruit by infrared-based fingerprinting
title_full_unstemmed	Characterization of antioxidant activity of Momordica Charantia fruit by infrared-based fingerprinting
title_sort	characterization of antioxidant activity of momordica charantia fruit by infrared-based fingerprinting
publisher	Taylor & Francis Group
publishDate	2017
url	http://irep.iium.edu.my/58997/ http://irep.iium.edu.my/58997/ http://irep.iium.edu.my/58997/ http://irep.iium.edu.my/58997/8/58997-Characterization%20of%20Antioxidant%20Activity.pdf http://irep.iium.edu.my/58997/7/58997-Characterization%20of%20Antioxidant%20Activity-SCOPUS.pdf
first_indexed	2023-09-18T21:23:30Z
last_indexed	2023-09-18T21:23:30Z
_version_	1777412038221365248

Characterization of antioxidant activity of Momordica Charantia fruit by infrared-based fingerprinting

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