MGMT and SPOCK2 promoter methylation in diffuse large B-Cell lymphoma: a study in two tertiary health centres in the East Coast of Malaysia = Metilasi promoter MGMT dan SPOCK2 dalam diffuse large B-cell lymphoma: satu kajian yang dijalankan di dua pusat Kesihatan di Pantai Timur Malaysia

MGMT (O6-Methylguanine-DNA Methyltransferase) suppresses tumor development by removing alkyl adduct, while SPOCK2 (SPARC/Osteonectin CWCV and Kazal-like domains proteoglycan) abolishes the inhibition of membrane-type matrix metalloproteinases (MT-MMP) which leads to angiogenesis. Hence, MGMT methyla...

Full description

Bibliographic Details
Main Authors: Zainuddin, Norafiza, Mohd. Ridah, Lailatul Jalilah, Omar, Aqilah Nabihah, A. Talib, Norlelawati, Muhammad, Siti Aesah @ Naznin, Hussain, Faezahtul Arbaeyah
Format: Article
Language:English
Published: Universiti Kebangsaan Malaysia 2017
Subjects:
Online Access:http://irep.iium.edu.my/56529/
http://irep.iium.edu.my/56529/
http://irep.iium.edu.my/56529/
http://irep.iium.edu.my/56529/1/56529_MGMT%20and%20SPOCK2%20Promoter%20Methylation.pdf