Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from clinacanthus nutans using subcritical carbon dioxide extraction

Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from clinacanthus nutans using subcritical carbon dioxide extraction

Subcritical carbon dioxide Soxhlet extraction of biologically active compounds from Clincanthus nutans was investigated by full factorial design to identify and optimize the factors (particle size and co-solvent) affecting extract yield, antioxidant activity, total phenolic content, total flavonoid...

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Main Authors: Alam, Md. Ariful, Sarker, Md. Zaidul Islam, Ghafoor, Kashif, Ferdosh, Sahena, Asing, Md. Eaqub Ali, Mirhosseini, Hamed, Yunus, Kamaruzzaman, Jahurul, Md. Haque Akanda, Khatib, Alfi
Format: Article
Language:English
English
English
Published: Taylor & Francis 2017
Subjects:
Q Science (General)
Online Access:http://irep.iium.edu.my/55587/
http://irep.iium.edu.my/55587/
http://irep.iium.edu.my/55587/
http://irep.iium.edu.my/55587/2/55587_Identification%20of%20bioactive%20compounds%20with%20GC%E2%80%93Q-TOF%E2%80%93MS_Scopus.pdf
http://irep.iium.edu.my/55587/3/55587_Identification%20of%20bioactive%20compounds%20with%20GC%E2%80%93Q-TOF%E2%80%93MS_WoS.pdf
http://irep.iium.edu.my/55587/15/55587_Identification%20of%20bioactive%20compounds.pdf
id iium-55587
recordtype eprints
spelling iium-555872018-03-22T00:31:19Z http://irep.iium.edu.my/55587/ Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from clinacanthus nutans using subcritical carbon dioxide extraction Alam, Md. Ariful Sarker, Md. Zaidul Islam Ghafoor, Kashif Ferdosh, Sahena Asing, Md. Eaqub Ali Mirhosseini, Hamed Yunus, Kamaruzzaman Jahurul, Md. Haque Akanda Khatib, Alfi Q Science (General) Subcritical carbon dioxide Soxhlet extraction of biologically active compounds from Clincanthus nutans was investigated by full factorial design to identify and optimize the factors (particle size and co-solvent) affecting extract yield, antioxidant activity, total phenolic content, total flavonoid content, and α-glucosidase inhibitory activity. An average of 3.103% yield, 98.90% antioxidant activity, 49.40 mg/g (GAE) TPC, 43.76 mg/g (RE), and 88.58% AGI activity can be achieved using the optimum levels of independent variables. The GC Q-TOF MS identification of optimized extract shown that different classes of phytoconstituents were successfully separated by CO2-Soxhlet to produce potential antioxidant and α-glucosidase inhibitory activity. Taylor & Francis 2017-03-24 Article PeerReviewed application/pdf en http://irep.iium.edu.my/55587/2/55587_Identification%20of%20bioactive%20compounds%20with%20GC%E2%80%93Q-TOF%E2%80%93MS_Scopus.pdf application/pdf en http://irep.iium.edu.my/55587/3/55587_Identification%20of%20bioactive%20compounds%20with%20GC%E2%80%93Q-TOF%E2%80%93MS_WoS.pdf application/pdf en http://irep.iium.edu.my/55587/15/55587_Identification%20of%20bioactive%20compounds.pdf Alam, Md. Ariful and Sarker, Md. Zaidul Islam and Ghafoor, Kashif and Ferdosh, Sahena and Asing, Md. Eaqub Ali and Mirhosseini, Hamed and Yunus, Kamaruzzaman and Jahurul, Md. Haque Akanda and Khatib, Alfi (2017) Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from clinacanthus nutans using subcritical carbon dioxide extraction. Separation Science and Technology, 52 (5). pp. 852-863. ISSN 0149-6395 E-ISSN 1520-5754 http://www.tandfonline.com/doi/abs/10.1080/01496395.2016.1271342?needAccess=true 10.1080/01496395.2016.1271342
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
English
topic Q Science (General)
spellingShingle Q Science (General)
Alam, Md. Ariful
Sarker, Md. Zaidul Islam
Ghafoor, Kashif
Ferdosh, Sahena
Asing, Md. Eaqub Ali
Mirhosseini, Hamed
Yunus, Kamaruzzaman
Jahurul, Md. Haque Akanda
Khatib, Alfi
Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from clinacanthus nutans using subcritical carbon dioxide extraction
description Subcritical carbon dioxide Soxhlet extraction of biologically active compounds from Clincanthus nutans was investigated by full factorial design to identify and optimize the factors (particle size and co-solvent) affecting extract yield, antioxidant activity, total phenolic content, total flavonoid content, and α-glucosidase inhibitory activity. An average of 3.103% yield, 98.90% antioxidant activity, 49.40 mg/g (GAE) TPC, 43.76 mg/g (RE), and 88.58% AGI activity can be achieved using the optimum levels of independent variables. The GC Q-TOF MS identification of optimized extract shown that different classes of phytoconstituents were successfully separated by CO2-Soxhlet to produce potential antioxidant and α-glucosidase inhibitory activity.
format Article
author Alam, Md. Ariful
Sarker, Md. Zaidul Islam
Ghafoor, Kashif
Ferdosh, Sahena
Asing, Md. Eaqub Ali
Mirhosseini, Hamed
Yunus, Kamaruzzaman
Jahurul, Md. Haque Akanda
Khatib, Alfi
author_facet Alam, Md. Ariful
Sarker, Md. Zaidul Islam
Ghafoor, Kashif
Ferdosh, Sahena
Asing, Md. Eaqub Ali
Mirhosseini, Hamed
Yunus, Kamaruzzaman
Jahurul, Md. Haque Akanda
Khatib, Alfi
author_sort Alam, Md. Ariful
title Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from clinacanthus nutans using subcritical carbon dioxide extraction
title_short Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from clinacanthus nutans using subcritical carbon dioxide extraction
title_full Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from clinacanthus nutans using subcritical carbon dioxide extraction
title_fullStr Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from clinacanthus nutans using subcritical carbon dioxide extraction
title_full_unstemmed Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from clinacanthus nutans using subcritical carbon dioxide extraction
title_sort identification of bioactive compounds with gc–q-tof–ms in the extracts from clinacanthus nutans using subcritical carbon dioxide extraction
publisher Taylor & Francis
publishDate 2017
url http://irep.iium.edu.my/55587/
http://irep.iium.edu.my/55587/
http://irep.iium.edu.my/55587/
http://irep.iium.edu.my/55587/2/55587_Identification%20of%20bioactive%20compounds%20with%20GC%E2%80%93Q-TOF%E2%80%93MS_Scopus.pdf
http://irep.iium.edu.my/55587/3/55587_Identification%20of%20bioactive%20compounds%20with%20GC%E2%80%93Q-TOF%E2%80%93MS_WoS.pdf
http://irep.iium.edu.my/55587/15/55587_Identification%20of%20bioactive%20compounds.pdf
first_indexed 2023-09-18T21:18:33Z
last_indexed 2023-09-18T21:18:33Z
_version_ 1777411726545780736

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