Methylation status of MGMT and SPOCK2 in diffuse large B-cell lymphoma
MGMT (O6-Methylguanine-DNA Methyltransferase) suppresses tumour development by removing alkyl adduct, while SPOCK2 (SPARC/Osteonectin CWCV and Kazal-like domains proteoglycan) abolishes the inhibition of membrane-type matrix metalloproteinases (MT-MMP) which leads to angiogenesis. Hence, MGMT methyl...
| Main Authors: | , , , , , |
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| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
2016
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/54375/ http://irep.iium.edu.my/54375/ http://irep.iium.edu.my/54375/1/54375_abstract.pdf |