Gaining more insight into the determinants of candida species pathogenicity in the oral cavity

Candida infection (candidiasis) is potentially life threatening and can occur in almost all anatomical sites, including the mouth. Candida species are in fact the most common fungal pathogens isolated from the oral cavity and frequently cause superficial infections such as oral candidiasis and dentu...

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Main Authors:	Arzmi, Mohd Hafiz, E., Alshwaimi, Wan Harun, Wan Himratul Aznita, Abdul Razak, Fathilah, Michael, McCullough, Nicola, Cirillo
Format:	Article
Language:	English English
Published:	Sage 2014
Subjects:	QR Microbiology RK Dentistry
Online Access:	http://irep.iium.edu.my/53620/ http://irep.iium.edu.my/53620/1/Gaining%20more%20insight%20into%20the%20determinants%20of%20Candida%20species%20pathogenicity%20in%20the%20oral%20cavity.pdf http://irep.iium.edu.my/53620/7/53620_Gaining%20more%20insight_SCOPUS.pdf

id	iium-53620
recordtype	eprints
spelling	iium-536202017-09-12T08:00:49Z http://irep.iium.edu.my/53620/ Gaining more insight into the determinants of candida species pathogenicity in the oral cavity Arzmi, Mohd Hafiz E., Alshwaimi Wan Harun, Wan Himratul Aznita Abdul Razak, Fathilah Michael, McCullough Nicola, Cirillo QR Microbiology RK Dentistry Candida infection (candidiasis) is potentially life threatening and can occur in almost all anatomical sites, including the mouth. Candida species are in fact the most common fungal pathogens isolated from the oral cavity and frequently cause superficial infections such as oral candidiasis and denture-associated erythematous stomatitis. Whilst systemic dissemination of Candida from intraoral foci is rare and largely due to severe deficits of the host immune defenses, the development of localized oral candidiasis is most commonly related to a variety of non-immune determinants such as Candida virulence factors and permissive oral microenvironment. In particular, phenotypic switching and dental biofilm have emerged as major determinants for the pathogenicity of Candida and are currently the subject ofintense research. An understanding of the molecular aspects underlying the biological behavior of Candida will be the key to the development of effective preventive as well as therapeutic measures for invasive and oral candidiasis. Sage 2014-03-17 Article PeerReviewed application/pdf en http://irep.iium.edu.my/53620/1/Gaining%20more%20insight%20into%20the%20determinants%20of%20Candida%20species%20pathogenicity%20in%20the%20oral%20cavity.pdf application/pdf en http://irep.iium.edu.my/53620/7/53620_Gaining%20more%20insight_SCOPUS.pdf Arzmi, Mohd Hafiz and E., Alshwaimi and Wan Harun, Wan Himratul Aznita and Abdul Razak, Fathilah and Michael, McCullough and Nicola, Cirillo (2014) Gaining more insight into the determinants of candida species pathogenicity in the oral cavity. European Journal of Inflammation, 12 (2). pp. 227-235. ISSN 1721-727X
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	QR Microbiology RK Dentistry
spellingShingle	QR Microbiology RK Dentistry Arzmi, Mohd Hafiz E., Alshwaimi Wan Harun, Wan Himratul Aznita Abdul Razak, Fathilah Michael, McCullough Nicola, Cirillo Gaining more insight into the determinants of candida species pathogenicity in the oral cavity
description	Candida infection (candidiasis) is potentially life threatening and can occur in almost all anatomical sites, including the mouth. Candida species are in fact the most common fungal pathogens isolated from the oral cavity and frequently cause superficial infections such as oral candidiasis and denture-associated erythematous stomatitis. Whilst systemic dissemination of Candida from intraoral foci is rare and largely due to severe deficits of the host immune defenses, the development of localized oral candidiasis is most commonly related to a variety of non-immune determinants such as Candida virulence factors and permissive oral microenvironment. In particular, phenotypic switching and dental biofilm have emerged as major determinants for the pathogenicity of Candida and are currently the subject ofintense research. An understanding of the molecular aspects underlying the biological behavior of Candida will be the key to the development of effective preventive as well as therapeutic measures for invasive and oral candidiasis.
format	Article
author	Arzmi, Mohd Hafiz E., Alshwaimi Wan Harun, Wan Himratul Aznita Abdul Razak, Fathilah Michael, McCullough Nicola, Cirillo
author_facet	Arzmi, Mohd Hafiz E., Alshwaimi Wan Harun, Wan Himratul Aznita Abdul Razak, Fathilah Michael, McCullough Nicola, Cirillo
author_sort	Arzmi, Mohd Hafiz
title	Gaining more insight into the determinants of candida species pathogenicity in the oral cavity
title_short	Gaining more insight into the determinants of candida species pathogenicity in the oral cavity
title_full	Gaining more insight into the determinants of candida species pathogenicity in the oral cavity
title_fullStr	Gaining more insight into the determinants of candida species pathogenicity in the oral cavity
title_full_unstemmed	Gaining more insight into the determinants of candida species pathogenicity in the oral cavity
title_sort	gaining more insight into the determinants of candida species pathogenicity in the oral cavity
publisher	Sage
publishDate	2014
url	http://irep.iium.edu.my/53620/ http://irep.iium.edu.my/53620/1/Gaining%20more%20insight%20into%20the%20determinants%20of%20Candida%20species%20pathogenicity%20in%20the%20oral%20cavity.pdf http://irep.iium.edu.my/53620/7/53620_Gaining%20more%20insight_SCOPUS.pdf
first_indexed	2023-09-18T21:15:51Z
last_indexed	2023-09-18T21:15:51Z
_version_	1777411556441587712

Gaining more insight into the determinants of candida species pathogenicity in the oral cavity

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