Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry

Clinacanthus nutans Lindau is known as snake grass belonging to the Acanthaceae family. This plant has diverse and potential medicinal uses in traditional herbal medicine for treating skin rashes, insects and snake bites, lesions caused by herpes simplex virus, diabetes, and gout in Malaysia, Indone...

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Main Authors:	Alam, Md Ariful, Ferdosh, Sahena, Ghafoor, Kashif, Hakim, Md Abdul, Juraimi, Abdul Shukor, Khatib, Alfi, Sarker, Md. Zaidul Islam
Format:	Article
Language:	English English
Published:	Elsevier (Singapore) Pte Ltd 2016
Subjects:	Q Science (General) RS Pharmacy and materia medica
Online Access:	http://irep.iium.edu.my/51511/ http://irep.iium.edu.my/51511/ http://irep.iium.edu.my/51511/ http://irep.iium.edu.my/51511/1/1-s2.0-S1995764516300116-main.pdf http://irep.iium.edu.my/51511/4/51511_Clinacanthus_nutans-_a_review_of_the_medicinal_WOS_and_SCOPUS.pdf

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recordtype	eprints
spelling	iium-515112017-04-05T03:33:45Z http://irep.iium.edu.my/51511/ Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry Alam, Md Ariful Ferdosh, Sahena Ghafoor, Kashif Hakim, Md Abdul Juraimi, Abdul Shukor Khatib, Alfi Sarker, Md. Zaidul Islam Q Science (General) RS Pharmacy and materia medica Clinacanthus nutans Lindau is known as snake grass belonging to the Acanthaceae family. This plant has diverse and potential medicinal uses in traditional herbal medicine for treating skin rashes, insects and snake bites, lesions caused by herpes simplex virus, diabetes, and gout in Malaysia, Indonesia, Thailand and China. Phytochemical investigations documented the varied contents of bioactive compounds from this plant namely flavonoids, glycosides, glycoglycerolipids, cerebrosides and monoacylmonogalatosylglycerol. The pharmacological experiment proved that various types of extracts and pure compounds from this species exhibited a broad range of biological properties such as anti-inflammatory, antiviral, antioxidant, and anti-diabetic activities. The findings of toxicity study showed that extracts from this plant did not show any toxicity thus it can be used as strong therapeutic agents for specific diseased conditions. However, further experiments on chemical components and their mode of action showing biological activities are required to elucidate the complete phytochemical profile and assess to confirm their suitability for future drugs. This review summarizes the medicinal uses, phytochemistry and pharmacology of this plant in order to explore its therapeutic potential and gaps necessitating for prospected research work. Elsevier (Singapore) Pte Ltd 2016-04 Article PeerReviewed application/pdf en http://irep.iium.edu.my/51511/1/1-s2.0-S1995764516300116-main.pdf application/pdf en http://irep.iium.edu.my/51511/4/51511_Clinacanthus_nutans-_a_review_of_the_medicinal_WOS_and_SCOPUS.pdf Alam, Md Ariful and Ferdosh, Sahena and Ghafoor, Kashif and Hakim, Md Abdul and Juraimi, Abdul Shukor and Khatib, Alfi and Sarker, Md. Zaidul Islam (2016) Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry. Asian Pacific Journal of Tropical Medicine, 9 (4). pp. 402-409. ISSN 1995-7645 http://www.sciencedirect.com/science/article/pii/S1995764516300116 10.1016/j.apjtm.2016.03.011
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	Q Science (General) RS Pharmacy and materia medica
spellingShingle	Q Science (General) RS Pharmacy and materia medica Alam, Md Ariful Ferdosh, Sahena Ghafoor, Kashif Hakim, Md Abdul Juraimi, Abdul Shukor Khatib, Alfi Sarker, Md. Zaidul Islam Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry
description	Clinacanthus nutans Lindau is known as snake grass belonging to the Acanthaceae family. This plant has diverse and potential medicinal uses in traditional herbal medicine for treating skin rashes, insects and snake bites, lesions caused by herpes simplex virus, diabetes, and gout in Malaysia, Indonesia, Thailand and China. Phytochemical investigations documented the varied contents of bioactive compounds from this plant namely flavonoids, glycosides, glycoglycerolipids, cerebrosides and monoacylmonogalatosylglycerol. The pharmacological experiment proved that various types of extracts and pure compounds from this species exhibited a broad range of biological properties such as anti-inflammatory, antiviral, antioxidant, and anti-diabetic activities. The findings of toxicity study showed that extracts from this plant did not show any toxicity thus it can be used as strong therapeutic agents for specific diseased conditions. However, further experiments on chemical components and their mode of action showing biological activities are required to elucidate the complete phytochemical profile and assess to confirm their suitability for future drugs. This review summarizes the medicinal uses, phytochemistry and pharmacology of this plant in order to explore its therapeutic potential and gaps necessitating for prospected research work.
format	Article
author	Alam, Md Ariful Ferdosh, Sahena Ghafoor, Kashif Hakim, Md Abdul Juraimi, Abdul Shukor Khatib, Alfi Sarker, Md. Zaidul Islam
author_facet	Alam, Md Ariful Ferdosh, Sahena Ghafoor, Kashif Hakim, Md Abdul Juraimi, Abdul Shukor Khatib, Alfi Sarker, Md. Zaidul Islam
author_sort	Alam, Md Ariful
title	Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry
title_short	Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry
title_full	Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry
title_fullStr	Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry
title_full_unstemmed	Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry
title_sort	clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry
publisher	Elsevier (Singapore) Pte Ltd
publishDate	2016
url	http://irep.iium.edu.my/51511/ http://irep.iium.edu.my/51511/ http://irep.iium.edu.my/51511/ http://irep.iium.edu.my/51511/1/1-s2.0-S1995764516300116-main.pdf http://irep.iium.edu.my/51511/4/51511_Clinacanthus_nutans-_a_review_of_the_medicinal_WOS_and_SCOPUS.pdf
first_indexed	2023-09-18T21:12:55Z
last_indexed	2023-09-18T21:12:55Z
_version_	1777411372752044032

Clinacanthus nutans: a review of the medicinal uses, pharmacology and phytochemistry

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