Clinical relevance of VKORC1 (G-1639A and C1173T) and CYP2C9*3 among patients on warfarin
What is known and Objectives: Testing for cytochrome P450-2C9 (CYP2C9) and vitamin K epoxide reductase complex subunit 1 (VKORC1) variant alleles is recommended by the FDA for dosing of warfarin. However, dose prediction models derived from data obtained in one population may not be applicable to a...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Blackwell Publishing
2011
|
Subjects: | |
Online Access: | http://irep.iium.edu.my/5105/ http://irep.iium.edu.my/5105/ http://irep.iium.edu.my/5105/2/Cyp2c9_and_VKROC.pdf |