Selection of potentially optimized trypsin variant with a more hydrophobic cluster active site via a phage display approach

Protein optimization can generally be obtained by rational enzyme design and directed evolution. Phage display has been used as a method for directed evolution. Trypsin has been studied as a biocatalyst in peptide synthesis despite its usual function in hydrolyzing peptide bonds. The objective of th...

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Bibliographic Details
Main Authors: Abdul Kudos, Muhammad Badri, Gissel, Sabrina, Bordusa, Frank
Format: Conference or Workshop Item
Language:English
English
Published: 2015
Subjects:
Online Access:http://irep.iium.edu.my/48397/
http://irep.iium.edu.my/48397/1/Badri%20KOP.pdf
http://irep.iium.edu.my/48397/2/Poster_badri_ACB2015.pdf