Design and in-vitro evaluation of sustained release floating tablets of metformin HCl based on effervescence and swelling
An oral sustained-release floating tablet formulation of metformin HCl was designed and developed. Effervescence and swelling properties were attributed on the developed tablets by sodium bicarbonate and HPMC-PEO polymer combination, respectively. Tablet composition was optimized by response surfa...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
School of Pharmacy, Shahid Beheshti University of Medical Sciences
2015
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/45505/ http://irep.iium.edu.my/45505/ http://irep.iium.edu.my/45505/3/Published_article_in_press.pdf http://irep.iium.edu.my/45505/4/Proof_Articles_in_Press.pdf |