Human topoisomerase II alpha as a prognostic biomarker in cancer chemotherapy
Topoisomerases are nuclear enzymes that regulate topology of DNA by facilitating the temporary cleavage and ligation cycle of DNA. Among all forms of topoisomerases, TOP-IIA is extensively associated with cell proliferation and therefore is an important therapeutic target in diseases that involved c...
| Main Authors: | , |
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| Format: | Article |
| Language: | English English |
| Published: |
Springer
2016
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/45324/ http://irep.iium.edu.my/45324/ http://irep.iium.edu.my/45324/ http://irep.iium.edu.my/45324/1/45324.pdf http://irep.iium.edu.my/45324/4/45324_Human%20topoisomerase%20II%20alpha%20as%20a%20prognostic%20biomarker%20in%20cancer%20chemotherapy_SCOPUS.pdf |