Cytotoxicity effect of melastoma malabatricum on skin melanoma and cervical cancer in vitro

Melastoma Malabatricum is a local shrub, commonly known as senduduk that belongs to the family of Melastomataceae. The aim is to evaluate the potential anticancer activities of the different extracts from M. malabathricum. In this study, petroleum ether and chloroform were used in the extraction of...

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Main Authors:	Ahmad Roslen, Nurfariza, Zainuddin, Norafiza, Kaderi, Mohd Arifin, Abdull Rasad, Mohammad Syaiful Bahari
Format:	Article
Language:	English
Published:	Bentham Open 2013
Subjects:	RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Online Access:	http://irep.iium.edu.my/43457/ http://irep.iium.edu.my/43457/ http://irep.iium.edu.my/43457/ http://irep.iium.edu.my/43457/1/TOPROCJ-4-4-249.pdf

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recordtype	eprints
spelling	iium-434572015-07-24T01:41:04Z http://irep.iium.edu.my/43457/ Cytotoxicity effect of melastoma malabatricum on skin melanoma and cervical cancer in vitro Ahmad Roslen, Nurfariza Zainuddin, Norafiza Kaderi, Mohd Arifin Abdull Rasad, Mohammad Syaiful Bahari RC0254 Neoplasms. Tumors. Oncology (including Cancer) Melastoma Malabatricum is a local shrub, commonly known as senduduk that belongs to the family of Melastomataceae. The aim is to evaluate the potential anticancer activities of the different extracts from M. malabathricum. In this study, petroleum ether and chloroform were used in the extraction of stems and flowers of M. malabathricum. The extracts were tested for cytotoxic activity against skin melanoma cancer cell lines (A375) and cervical cancer cell lines (HeLa). Petroleum ether extracts of stem (PeMMS) showed significant growth inhibition of A375 cell lines, followed by the extract of flower (PeMMF). Meanwhile, PeMMF showed less significant growth inhibition of HeLa cell lines, followed by PeMMS. As for the chloroform extracts of stem (CHMMS) and flower (CHMMF), it does not inhibit the growth of both cell lines. Bentham Open 2013 Article PeerReviewed application/pdf en http://irep.iium.edu.my/43457/1/TOPROCJ-4-4-249.pdf Ahmad Roslen, Nurfariza and Zainuddin, Norafiza and Kaderi, Mohd Arifin and Abdull Rasad, Mohammad Syaiful Bahari (2013) Cytotoxicity effect of melastoma malabatricum on skin melanoma and cervical cancer in vitro. The Open Conference Proceedings Journal, 4. p. 249. ISSN 2210-2892 http://benthamopen.com/ABSTRACT/TOPROCJ-4-4-249 http://10.2174/2210289201304010249
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RC0254 Neoplasms. Tumors. Oncology (including Cancer)
spellingShingle	RC0254 Neoplasms. Tumors. Oncology (including Cancer) Ahmad Roslen, Nurfariza Zainuddin, Norafiza Kaderi, Mohd Arifin Abdull Rasad, Mohammad Syaiful Bahari Cytotoxicity effect of melastoma malabatricum on skin melanoma and cervical cancer in vitro
description	Melastoma Malabatricum is a local shrub, commonly known as senduduk that belongs to the family of Melastomataceae. The aim is to evaluate the potential anticancer activities of the different extracts from M. malabathricum. In this study, petroleum ether and chloroform were used in the extraction of stems and flowers of M. malabathricum. The extracts were tested for cytotoxic activity against skin melanoma cancer cell lines (A375) and cervical cancer cell lines (HeLa). Petroleum ether extracts of stem (PeMMS) showed significant growth inhibition of A375 cell lines, followed by the extract of flower (PeMMF). Meanwhile, PeMMF showed less significant growth inhibition of HeLa cell lines, followed by PeMMS. As for the chloroform extracts of stem (CHMMS) and flower (CHMMF), it does not inhibit the growth of both cell lines.
format	Article
author	Ahmad Roslen, Nurfariza Zainuddin, Norafiza Kaderi, Mohd Arifin Abdull Rasad, Mohammad Syaiful Bahari
author_facet	Ahmad Roslen, Nurfariza Zainuddin, Norafiza Kaderi, Mohd Arifin Abdull Rasad, Mohammad Syaiful Bahari
author_sort	Ahmad Roslen, Nurfariza
title	Cytotoxicity effect of melastoma malabatricum on skin melanoma and cervical cancer in vitro
title_short	Cytotoxicity effect of melastoma malabatricum on skin melanoma and cervical cancer in vitro
title_full	Cytotoxicity effect of melastoma malabatricum on skin melanoma and cervical cancer in vitro
title_fullStr	Cytotoxicity effect of melastoma malabatricum on skin melanoma and cervical cancer in vitro
title_full_unstemmed	Cytotoxicity effect of melastoma malabatricum on skin melanoma and cervical cancer in vitro
title_sort	cytotoxicity effect of melastoma malabatricum on skin melanoma and cervical cancer in vitro
publisher	Bentham Open
publishDate	2013
url	http://irep.iium.edu.my/43457/ http://irep.iium.edu.my/43457/ http://irep.iium.edu.my/43457/ http://irep.iium.edu.my/43457/1/TOPROCJ-4-4-249.pdf
first_indexed	2023-09-18T21:01:54Z
last_indexed	2023-09-18T21:01:54Z
_version_	1777410679587733504

Cytotoxicity effect of melastoma malabatricum on skin melanoma and cervical cancer in vitro

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