In vitro antifilarial potential of the flower and stem extracts of Leucas cephalotes on cattle filarial parasite Setaria cervi
Objective: To assess the potential antifilarial activity of the aqueous and alcoholic extracts of flower and stem prepared from L. cephalotes. Materials and methods: The effect of extracts was studied on the spontaneous movements of wholeworm and the nerve-muscle preparation of Setaria cervi and o...
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Natural Remedies, Bangalore, India.
2002
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| Online Access: | http://irep.iium.edu.my/40992/ http://irep.iium.edu.my/40992/ http://irep.iium.edu.my/40992/1/In_vitro_antifilarial_potential_of_the_flower_and_stems_extracts_of_Leucas_cephalotes.pdf |
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iium-409922015-03-11T01:02:24Z http://irep.iium.edu.my/40992/ In vitro antifilarial potential of the flower and stem extracts of Leucas cephalotes on cattle filarial parasite Setaria cervi Ahmed, Qamar Uddin Parveen, Nazneen Khan, N. U. Singhal, K. C. Q Science (General) Objective: To assess the potential antifilarial activity of the aqueous and alcoholic extracts of flower and stem prepared from L. cephalotes. Materials and methods: The effect of extracts was studied on the spontaneous movements of wholeworm and the nerve-muscle preparation of Setaria cervi and on the survival of microfilariae in vitro. Results: Alcoholic extracts of the flower and stem caused inhibition of the spontaneous movements of the wholeworm and of the nerve-muscle preparation of S. cervi. However, aqueous extracts of the flower and stem failed to modify the movements of the whole worm while caused irreversible paralysis of nerve muscle preparation characterized by decrease in rate, tone and amplitude of contractions. This may be due to failure of penetration of cuticular barrier by the aqueous extract. The alcoholic extract also decreased the duration of survival of microfilariae of S.cervi. Conclusion: L. cephalotes exhibits potential antifilarial activity against both the adult worms and the microfilariae of Setaria cervi. Further work is required to find its utility in human filarial infections. Keyword: Leucas cephalotes, Setaria cervi antifilarial activity, microfilaricidal. Natural Remedies, Bangalore, India. 2002-06 Article PeerReviewed application/pdf en http://irep.iium.edu.my/40992/1/In_vitro_antifilarial_potential_of_the_flower_and_stems_extracts_of_Leucas_cephalotes.pdf Ahmed, Qamar Uddin and Parveen, Nazneen and Khan, N. U. and Singhal, K. C. (2002) In vitro antifilarial potential of the flower and stem extracts of Leucas cephalotes on cattle filarial parasite Setaria cervi. Journal of Natural Remedies, 2 (2). pp. 155-163. ISSN 0972-5547 http://www.jnronline.com/index.php/jnr/article/view/28821 |
| repository_type |
Digital Repository |
| institution_category |
Local University |
| institution |
International Islamic University Malaysia |
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IIUM Repository |
| collection |
Online Access |
| language |
English |
| topic |
Q Science (General) |
| spellingShingle |
Q Science (General) Ahmed, Qamar Uddin Parveen, Nazneen Khan, N. U. Singhal, K. C. In vitro antifilarial potential of the flower and stem extracts of Leucas cephalotes on cattle filarial parasite Setaria cervi |
| description |
Objective: To assess the potential antifilarial activity of the aqueous and alcoholic extracts of flower
and stem prepared from L. cephalotes. Materials and methods: The effect of extracts was studied on the
spontaneous movements of wholeworm and the nerve-muscle preparation of Setaria cervi and on the
survival of microfilariae in vitro. Results: Alcoholic extracts of the flower and stem caused inhibition of
the spontaneous movements of the wholeworm and of the nerve-muscle preparation of S. cervi. However,
aqueous extracts of the flower and stem failed to modify the movements of the whole worm while caused
irreversible paralysis of nerve muscle preparation characterized by decrease in rate, tone and amplitude
of contractions. This may be due to failure of penetration of cuticular barrier by the aqueous extract.
The alcoholic extract also decreased the duration of survival of microfilariae of S.cervi. Conclusion:
L. cephalotes exhibits potential antifilarial activity against both the adult worms and the microfilariae
of Setaria cervi. Further work is required to find its utility in human filarial infections.
Keyword: Leucas cephalotes, Setaria cervi antifilarial activity, microfilaricidal. |
| format |
Article |
| author |
Ahmed, Qamar Uddin Parveen, Nazneen Khan, N. U. Singhal, K. C. |
| author_facet |
Ahmed, Qamar Uddin Parveen, Nazneen Khan, N. U. Singhal, K. C. |
| author_sort |
Ahmed, Qamar Uddin |
| title |
In vitro antifilarial potential of the flower and stem extracts of Leucas cephalotes on cattle filarial parasite Setaria cervi |
| title_short |
In vitro antifilarial potential of the flower and stem extracts of Leucas cephalotes on cattle filarial parasite Setaria cervi |
| title_full |
In vitro antifilarial potential of the flower and stem extracts of Leucas cephalotes on cattle filarial parasite Setaria cervi |
| title_fullStr |
In vitro antifilarial potential of the flower and stem extracts of Leucas cephalotes on cattle filarial parasite Setaria cervi |
| title_full_unstemmed |
In vitro antifilarial potential of the flower and stem extracts of Leucas cephalotes on cattle filarial parasite Setaria cervi |
| title_sort |
in vitro antifilarial potential of the flower and stem extracts of leucas cephalotes on cattle filarial parasite setaria cervi |
| publisher |
Natural Remedies, Bangalore, India. |
| publishDate |
2002 |
| url |
http://irep.iium.edu.my/40992/ http://irep.iium.edu.my/40992/ http://irep.iium.edu.my/40992/1/In_vitro_antifilarial_potential_of_the_flower_and_stems_extracts_of_Leucas_cephalotes.pdf |
| first_indexed |
2023-09-18T20:58:43Z |
| last_indexed |
2023-09-18T20:58:43Z |
| _version_ |
1777410479279308800 |