Computer Aided Design of potential inhibitors for Gaucher disease

Acid β-glucosidase (GlcCerase) is a lysosomal enzyme, which is important in biodegradation of blood cells in human body. Mutation of GlcCerase will lead to Gaucher disease; the most common lysosomal storage disease. The current available treatments for Gaucher disease are enzyme replacement therapy...

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Bibliographic Details
Main Authors: Noorbatcha, Ibrahim Ali, Mohd. Salleh, Hamzah
Format: Conference or Workshop Item
Language:English
Published: 2010
Subjects:
Online Access:http://irep.iium.edu.my/4074/
http://irep.iium.edu.my/4074/4/IRIIE-CAD_Gaucher.pdf