Adiponectin correlates in Malaysians: a comparison of metabolic syndrome and healthy respondents

Several studies have demonstrated that adiponectin has strong association with metabolic syndrome and its factors like obesity, insulin resistance, type 2 diabetes, dyslipidemia and coronary artery disease. A total 152 subjects were registered in this study. Among the respondents 76 were with metabo...

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Main Authors: Md Aris, Mohd Aznan, Khattak, Muhammad Muzaffar Ali Khan, Abdullah, Nor Zamzila, Mohd Rus, Razman, Draman, Samsul
Format: Article
Language:English
Published: Science and Education Publishing 2014
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Online Access:http://irep.iium.edu.my/40261/
http://irep.iium.edu.my/40261/
http://irep.iium.edu.my/40261/
http://irep.iium.edu.my/40261/1/Adiponectin_Correlates_in_Malaysian_s-ajcmr-2-6-1.pdf
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spelling iium-402612016-02-25T03:07:32Z http://irep.iium.edu.my/40261/ Adiponectin correlates in Malaysians: a comparison of metabolic syndrome and healthy respondents Md Aris, Mohd Aznan Khattak, Muhammad Muzaffar Ali Khan Abdullah, Nor Zamzila Mohd Rus, Razman Draman, Samsul R Medicine (General) Several studies have demonstrated that adiponectin has strong association with metabolic syndrome and its factors like obesity, insulin resistance, type 2 diabetes, dyslipidemia and coronary artery disease. A total 152 subjects were registered in this study. Among the respondents 76 were with metabolic syndrome (based on the criteria of the International Diabetes Federation (IDF) world-wide definition) and another 76 matching healthy respondents. The factors which were studied for possible differences and association include central obesity (body mass index (BMI) & waist circumference (WC), hypertension (systolic blood pressure (SBP), diastolic blood pressure (DBP), dyslipidemia (total cholesterol (Tc), high density lipoprotein Cholesterol (HDL-c), low density lipoprotein Cholesterol (LDL-c), Triglyceride (TG) and Adiponectin (AD), fasting plasma glucose and history of smoking. The data collected was statistically analyzed using SPSS statistical software version 12.0. Two tests were performed including paired t-test and Pearson correlation analysis. The collected data revealed some interesting differences for the healthy and metabolic syndrome respondents. There were significant (P<0.01) differences for central obesity and hypertension. There were also significant (P<0.01, P<0.1, P<0.01) differences for TG, HDL and fasting plasma glucose. More importantly, AD concentration was significantly (P<0.05) higher in normal healthy respondents. The AD showed strong negative association (r = - 2.91, P<0.001) with FBG and positive association (r = 2.89, P<0.001) with HDL-c. The present study provides baseline information on the predication of metabolic syndrome in Malaysian population. Science and Education Publishing 2014 Article PeerReviewed application/pdf en http://irep.iium.edu.my/40261/1/Adiponectin_Correlates_in_Malaysian_s-ajcmr-2-6-1.pdf Md Aris, Mohd Aznan and Khattak, Muhammad Muzaffar Ali Khan and Abdullah, Nor Zamzila and Mohd Rus, Razman and Draman, Samsul (2014) Adiponectin correlates in Malaysians: a comparison of metabolic syndrome and healthy respondents. American Journal of Clinical Medicine Research, 2 (6). pp. 106-110. ISSN 2328-4005 (P), 2328-403X (o) http://pubs.sciepub.com/ajcmr/2/6/1/ 10.12691/ajcmr-2-6-1
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic R Medicine (General)
spellingShingle R Medicine (General)
Md Aris, Mohd Aznan
Khattak, Muhammad Muzaffar Ali Khan
Abdullah, Nor Zamzila
Mohd Rus, Razman
Draman, Samsul
Adiponectin correlates in Malaysians: a comparison of metabolic syndrome and healthy respondents
description Several studies have demonstrated that adiponectin has strong association with metabolic syndrome and its factors like obesity, insulin resistance, type 2 diabetes, dyslipidemia and coronary artery disease. A total 152 subjects were registered in this study. Among the respondents 76 were with metabolic syndrome (based on the criteria of the International Diabetes Federation (IDF) world-wide definition) and another 76 matching healthy respondents. The factors which were studied for possible differences and association include central obesity (body mass index (BMI) & waist circumference (WC), hypertension (systolic blood pressure (SBP), diastolic blood pressure (DBP), dyslipidemia (total cholesterol (Tc), high density lipoprotein Cholesterol (HDL-c), low density lipoprotein Cholesterol (LDL-c), Triglyceride (TG) and Adiponectin (AD), fasting plasma glucose and history of smoking. The data collected was statistically analyzed using SPSS statistical software version 12.0. Two tests were performed including paired t-test and Pearson correlation analysis. The collected data revealed some interesting differences for the healthy and metabolic syndrome respondents. There were significant (P<0.01) differences for central obesity and hypertension. There were also significant (P<0.01, P<0.1, P<0.01) differences for TG, HDL and fasting plasma glucose. More importantly, AD concentration was significantly (P<0.05) higher in normal healthy respondents. The AD showed strong negative association (r = - 2.91, P<0.001) with FBG and positive association (r = 2.89, P<0.001) with HDL-c. The present study provides baseline information on the predication of metabolic syndrome in Malaysian population.
format Article
author Md Aris, Mohd Aznan
Khattak, Muhammad Muzaffar Ali Khan
Abdullah, Nor Zamzila
Mohd Rus, Razman
Draman, Samsul
author_facet Md Aris, Mohd Aznan
Khattak, Muhammad Muzaffar Ali Khan
Abdullah, Nor Zamzila
Mohd Rus, Razman
Draman, Samsul
author_sort Md Aris, Mohd Aznan
title Adiponectin correlates in Malaysians: a comparison of metabolic syndrome and healthy respondents
title_short Adiponectin correlates in Malaysians: a comparison of metabolic syndrome and healthy respondents
title_full Adiponectin correlates in Malaysians: a comparison of metabolic syndrome and healthy respondents
title_fullStr Adiponectin correlates in Malaysians: a comparison of metabolic syndrome and healthy respondents
title_full_unstemmed Adiponectin correlates in Malaysians: a comparison of metabolic syndrome and healthy respondents
title_sort adiponectin correlates in malaysians: a comparison of metabolic syndrome and healthy respondents
publisher Science and Education Publishing
publishDate 2014
url http://irep.iium.edu.my/40261/
http://irep.iium.edu.my/40261/
http://irep.iium.edu.my/40261/
http://irep.iium.edu.my/40261/1/Adiponectin_Correlates_in_Malaysian_s-ajcmr-2-6-1.pdf
first_indexed 2023-09-18T20:57:45Z
last_indexed 2023-09-18T20:57:45Z
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