Clinicopathological features of homologous recombination deficient epithelial ovarian cancers: sensitivity to PARP inhibitors, platinum and survival

Up to 50% of epithelial ovarian cancers (EOC) display defects in the homologous recombination (HR) pathway. We sought to determine the ramifications of the homologous recombination deficient (HRD) status on the clinicopathological features, chemotherapy response and survival outcomes of EOC patie...

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Bibliographic Details
Main Authors: Mukhophadyay, Asima, Plummer, Elizabeth R, Elattar, Ahmed, San, SooHoo, Uzir, Bisha Fathamah, Quinn, Jennifer E, Edmondson, Richard J, Curtin, Nicola J, Harriet, Aneke, Maxwell, Perry, McCluggage, W Glenn
Format: Article
Language:English
Published: American Association of Cancer Research 2012
Subjects:
Online Access:http://irep.iium.edu.my/33769/
http://irep.iium.edu.my/33769/
http://irep.iium.edu.my/33769/
http://irep.iium.edu.my/33769/1/33769.pdf