Mechanical loading response in trabecular bone is abrogated by sclerostin - A direct demonstration

Sclerostin is expressed almost exclusively by mature osteocytes in bone. Recent findings from this lab indicate that sclerostin targets pre-osteocytes and osteocytes to regulate bone mineralisation(1), osteoclast activity(2), and, potentially, osteocytic osteolysis(3). Sclerostin expression in vivo...

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Bibliographic Details
Main Authors: Khalid, Kamarul Ariffin, Kogawa, Masakazu, Wijenayaka, Asiri R, Findlay, David M, Atkins, Gerald J
Format: Conference or Workshop Item
Language:English
English
English
Published: Australian Health and Medical Research Council 2012
Subjects:
Online Access:http://irep.iium.edu.my/29838/
http://irep.iium.edu.my/29838/17/29838%20-abstract.PDF
http://irep.iium.edu.my/29838/1/AHMRC_2012_Poster_Kamarul_Final.pdf
http://irep.iium.edu.my/29838/2/AHMRC_2012_Kamarul_Final.pdf