Anti-Proliferation Effects of Benzimidazole Derivatives on HCT-116 Colon Cancer and MCF-7 Breast Cancer Cell Lines

Benzimidazoles 1-4 were obtained using modified synthesis methods and studied for their ability to inhibit cell proliferation of colon cancer cell HCT-116 and breast cancer cell MCF-7 using MTT assays. In the HCT-116 cell line, benzimidazole 2 was found to have an IC50 value of 16.2±3.85 μg/mL and...

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Bibliographic Details
Main Authors: Al-Douh, Mohammed Hadi, Sahib, Hayder, Osman, Hasnah, Abd Hamid, Shafida, Salhimi, Salizawati M
Format: Article
Language:English
Published: National Cancer Center, Korea. 2012
Subjects:
Online Access:http://irep.iium.edu.my/28843/
http://irep.iium.edu.my/28843/
http://irep.iium.edu.my/28843/
http://irep.iium.edu.my/28843/1/Anti-Proliferation_Effects_of_Benzimidazole_Derivatives_on.pdf