High initial burst release of gentamicin formulated as PLGA microspheres implant for treating orthopaedic infection
Antibiotic treatment of orthopaedic infection is complicated by systemic toxicity and the need of effective therapeutic concentration necessary to ensure optimum killing of bacteria. To overcome the problem of systemic toxicity and to achieve a high initial release followed by sustained release of a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Academic Sciences
2012
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/25825/ http://irep.iium.edu.my/25825/ http://irep.iium.edu.my/25825/1/High_burst_release_gentamicin_formulated_as_PLGAmicrospheres.pdf |