Yam contributes to improvement of glucose metabolism in rats

To investigate whether yam improves glucose metabolism, yam-containing diets were given to Wistar rats. In a short-term experiment, fasted-rats were given 1.0 g of a control and 20% yam-containing diets. At 60 min after start of the feeding, glucose level in the yam diet group was lower or tend...

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Main Authors:	Hashimoto, Naoto, Noda, Takahiro, Kim, Sun-Ju, Sarker, Md. Zaidul Islam, Yamauchi, Hiroaki, Takigawa, Shigenobu, Matsuura-Endo, Chie, Suzuki, Tatsuro, Han, Kyu-Ho, Fukushima, Michihiro
Format:	Article
Language:	English
Published:	Springer 2009
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/24849/ http://irep.iium.edu.my/24849/ http://irep.iium.edu.my/24849/ http://irep.iium.edu.my/24849/1/fulltext.pdf

id	iium-24849
recordtype	eprints
spelling	iium-248492013-01-17T08:04:47Z http://irep.iium.edu.my/24849/ Yam contributes to improvement of glucose metabolism in rats Hashimoto, Naoto Noda, Takahiro Kim, Sun-Ju Sarker, Md. Zaidul Islam Yamauchi, Hiroaki Takigawa, Shigenobu Matsuura-Endo, Chie Suzuki, Tatsuro Han, Kyu-Ho Fukushima, Michihiro QD Chemistry To investigate whether yam improves glucose metabolism, yam-containing diets were given to Wistar rats. In a short-term experiment, fasted-rats were given 1.0 g of a control and 20% yam-containing diets. At 60 min after start of the feeding, glucose level in the yam diet group was lower or tended to be lower than that in the control diet. Insulin levels at 30 min and 60 min were significantly lower than those in the control group. In a long-term experiment, a normal diet (N) or 25% high fat diets with (Y) or without 15% yam powder (HF) were given to rats for 4 weeks. At 4 weeks, in an oral glucose tolerance test, the area under the curve (AUC) of plasma glucose level was higher in the HF group than that in the N group, whereas those in the Y groups did not differ from that in the N group. Glycosylated hemoglobin levels had similar tendency to the AUCs. Plasma leptin levels in the Y groups were significantly higher than that in the N group. In conclusion, yam may contribute to improvement of glucose metabolism. Additionally, we speculated that leptin level is possibly involved in the insulin-response to yam diets. Springer 2009 Article PeerReviewed application/pdf en cc_by_nd http://irep.iium.edu.my/24849/1/fulltext.pdf Hashimoto, Naoto and Noda, Takahiro and Kim, Sun-Ju and Sarker, Md. Zaidul Islam and Yamauchi, Hiroaki and Takigawa, Shigenobu and Matsuura-Endo, Chie and Suzuki, Tatsuro and Han, Kyu-Ho and Fukushima, Michihiro (2009) Yam contributes to improvement of glucose metabolism in rats. Plant Foods for Human Nutrition, 64 (3). pp. 193-198. ISSN 0921-9668 http://dx.doi.org/10.1007/s11130-009-0126-z doi:10.1007/s11130-009-0126-z
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QD Chemistry
spellingShingle	QD Chemistry Hashimoto, Naoto Noda, Takahiro Kim, Sun-Ju Sarker, Md. Zaidul Islam Yamauchi, Hiroaki Takigawa, Shigenobu Matsuura-Endo, Chie Suzuki, Tatsuro Han, Kyu-Ho Fukushima, Michihiro Yam contributes to improvement of glucose metabolism in rats
description	To investigate whether yam improves glucose metabolism, yam-containing diets were given to Wistar rats. In a short-term experiment, fasted-rats were given 1.0 g of a control and 20% yam-containing diets. At 60 min after start of the feeding, glucose level in the yam diet group was lower or tended to be lower than that in the control diet. Insulin levels at 30 min and 60 min were significantly lower than those in the control group. In a long-term experiment, a normal diet (N) or 25% high fat diets with (Y) or without 15% yam powder (HF) were given to rats for 4 weeks. At 4 weeks, in an oral glucose tolerance test, the area under the curve (AUC) of plasma glucose level was higher in the HF group than that in the N group, whereas those in the Y groups did not differ from that in the N group. Glycosylated hemoglobin levels had similar tendency to the AUCs. Plasma leptin levels in the Y groups were significantly higher than that in the N group. In conclusion, yam may contribute to improvement of glucose metabolism. Additionally, we speculated that leptin level is possibly involved in the insulin-response to yam diets.
format	Article
author	Hashimoto, Naoto Noda, Takahiro Kim, Sun-Ju Sarker, Md. Zaidul Islam Yamauchi, Hiroaki Takigawa, Shigenobu Matsuura-Endo, Chie Suzuki, Tatsuro Han, Kyu-Ho Fukushima, Michihiro
author_facet	Hashimoto, Naoto Noda, Takahiro Kim, Sun-Ju Sarker, Md. Zaidul Islam Yamauchi, Hiroaki Takigawa, Shigenobu Matsuura-Endo, Chie Suzuki, Tatsuro Han, Kyu-Ho Fukushima, Michihiro
author_sort	Hashimoto, Naoto
title	Yam contributes to improvement of glucose metabolism in rats
title_short	Yam contributes to improvement of glucose metabolism in rats
title_full	Yam contributes to improvement of glucose metabolism in rats
title_fullStr	Yam contributes to improvement of glucose metabolism in rats
title_full_unstemmed	Yam contributes to improvement of glucose metabolism in rats
title_sort	yam contributes to improvement of glucose metabolism in rats
publisher	Springer
publishDate	2009
url	http://irep.iium.edu.my/24849/ http://irep.iium.edu.my/24849/ http://irep.iium.edu.my/24849/ http://irep.iium.edu.my/24849/1/fulltext.pdf
first_indexed	2023-09-18T20:37:09Z
last_indexed	2023-09-18T20:37:09Z
_version_	1777409122243706880

Yam contributes to improvement of glucose metabolism in rats

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