Yam contributes to improvement of glucose metabolism in rats
To investigate whether yam improves glucose metabolism, yam-containing diets were given to Wistar rats. In a short-term experiment, fasted-rats were given 1.0 g of a control and 20% yam-containing diets. At 60 min after start of the feeding, glucose level in the yam diet group was lower or tend...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer
2009
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/24849/ http://irep.iium.edu.my/24849/ http://irep.iium.edu.my/24849/ http://irep.iium.edu.my/24849/1/fulltext.pdf |
| Summary: | To investigate whether yam improves glucose
metabolism, yam-containing diets were given to Wistar rats.
In a short-term experiment, fasted-rats were given 1.0 g of a
control and 20% yam-containing diets. At 60 min after start
of the feeding, glucose level in the yam diet group was
lower or tended to be lower than that in the control diet.
Insulin levels at 30 min and 60 min were significantly
lower than those in the control group. In a long-term
experiment, a normal diet (N) or 25% high fat diets with
(Y) or without 15% yam powder (HF) were given to rats for
4 weeks. At 4 weeks, in an oral glucose tolerance test, the
area under the curve (AUC) of plasma glucose level was
higher in the HF group than that in the N group, whereas
those in the Y groups did not differ from that in the N
group. Glycosylated hemoglobin levels had similar tendency
to the AUCs. Plasma leptin levels in the Y groups were
significantly higher than that in the N group. In conclusion,
yam may contribute to improvement of glucose metabolism.
Additionally, we speculated that leptin level is
possibly involved in the insulin-response to yam diets. |
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