Copper

Copper is one of the few native metals, meaning metals that occur naturally in a directly usable, unalloyed metallic form. This led to very early human use in several regions, from . Thousands of years later, it was the first metal to be smelted from sulfide ores, ; the first metal to be cast into a shape in a mold, ; and the first metal to be purposely alloyed with another metal, tin, to create bronze, .
Commonly encountered compounds are copper(II) salts, which often impart blue or green colors to such minerals as azurite, malachite, and turquoise, and have been used widely and historically as pigments.
Copper used in buildings, usually for roofing, oxidizes to form a green patina of compounds called verdigris. Copper is sometimes used in decorative art, both in its elemental metal form and in compounds as pigments. Copper compounds are used as bacteriostatic agents, fungicides, and wood preservatives.
Copper is essential to all aerobic organisms. It is particularly associated with oxygen metabolism. For example, it is found in the respiratory enzyme complex cytochrome c oxidase, in the oxygen carrying hemocyanin, and in several hydroxylases. Adult humans contain between 1.4 and 2.1 mg of copper per kilogram of body weight.
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