In Vitro Antibacterial Activity of Eurycoma Longifolia Jack (Tongkat Ali) Root Extract

In Vitro Antibacterial Activity of Eurycoma Longifolia Jack (Tongkat Ali) Root Extract

Introduction: Currently, researchers are aiming to explore herbal plants to replace synthetic drugs because herbal plants contain high active compounds and fewer side effects. Our study was done to determine the antibacterial activity of Eurycoma longifolia Jack (E. longifolia) root using ethanol ba...

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Main Authors: Najmuldeen, Ghazi Faisal, G. G., Faisal, S. M., Zakaria
Format: Article
Language:English
Published: 2015
Subjects:
TP Chemical technology
Online Access:http://umpir.ump.edu.my/id/eprint/9418/
http://umpir.ump.edu.my/id/eprint/9418/
http://umpir.ump.edu.my/id/eprint/9418/1/In%20Vitro%20Antibacterial%20Activity%20of%20Eurycoma%20Longifolia%20Jack%20%28Tongkat%20Ali%29%20Root%20Extract.pdf
id ump-9418
recordtype eprints
spelling ump-94182016-04-13T02:00:22Z http://umpir.ump.edu.my/id/eprint/9418/ In Vitro Antibacterial Activity of Eurycoma Longifolia Jack (Tongkat Ali) Root Extract Najmuldeen, Ghazi Faisal G. G., Faisal S. M., Zakaria TP Chemical technology Introduction: Currently, researchers are aiming to explore herbal plants to replace synthetic drugs because herbal plants contain high active compounds and fewer side effects. Our study was done to determine the antibacterial activity of Eurycoma longifolia Jack (E. longifolia) root using ethanol based extract. Methods: Five types of pathogenic bacterial strains were used; Gram-positive (Staphylococcus aureus and Bacillus cereus) and Gram-negative (Escherichia coli, Salmonella typhi and Pseudomonas aeruginosa). Disc diffusion assay and Minimum Inhibitory Concentration (MIC) tests were used to determine the inhibition zone and turbidity of suspension which reflects the antibacterial activity of the extract. Results: The ethanolic extract of E. longifolia Jack root extract showed positive results against Gram-positive bacteria (S. aureus and B. cereus) and Gramnegative (S. typhi). B.cereus and S.typhi showed inhibition zone values of 11.76mm and 14.33mm at the extract concentration of 150mg/ml that were higher than the positive control values (9.00, 12.67mm) respectively. However, E. coli and P. aeruginosa did not show any inhibition by the ethanol-based extract. Conclusion: From the results we can conclude that E.Longifolia root extract possesses antibacterial activity that can be further explored to produce new medicinal products. 2015 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/9418/1/In%20Vitro%20Antibacterial%20Activity%20of%20Eurycoma%20Longifolia%20Jack%20%28Tongkat%20Ali%29%20Root%20Extract.pdf Najmuldeen, Ghazi Faisal and G. G., Faisal and S. M., Zakaria (2015) In Vitro Antibacterial Activity of Eurycoma Longifolia Jack (Tongkat Ali) Root Extract. The International Medical Journal Malaysia, 14 (1). pp. 77-81. http://journals.iium.edu.my/imjm/index.php/eimj/article/view/225
repository_type Digital Repository
institution_category Local University
institution Universiti Malaysia Pahang
building UMP Institutional Repository
collection Online Access
language English
topic TP Chemical technology
spellingShingle TP Chemical technology
Najmuldeen, Ghazi Faisal
G. G., Faisal
S. M., Zakaria
In Vitro Antibacterial Activity of Eurycoma Longifolia Jack (Tongkat Ali) Root Extract
description Introduction: Currently, researchers are aiming to explore herbal plants to replace synthetic drugs because herbal plants contain high active compounds and fewer side effects. Our study was done to determine the antibacterial activity of Eurycoma longifolia Jack (E. longifolia) root using ethanol based extract. Methods: Five types of pathogenic bacterial strains were used; Gram-positive (Staphylococcus aureus and Bacillus cereus) and Gram-negative (Escherichia coli, Salmonella typhi and Pseudomonas aeruginosa). Disc diffusion assay and Minimum Inhibitory Concentration (MIC) tests were used to determine the inhibition zone and turbidity of suspension which reflects the antibacterial activity of the extract. Results: The ethanolic extract of E. longifolia Jack root extract showed positive results against Gram-positive bacteria (S. aureus and B. cereus) and Gramnegative (S. typhi). B.cereus and S.typhi showed inhibition zone values of 11.76mm and 14.33mm at the extract concentration of 150mg/ml that were higher than the positive control values (9.00, 12.67mm) respectively. However, E. coli and P. aeruginosa did not show any inhibition by the ethanol-based extract. Conclusion: From the results we can conclude that E.Longifolia root extract possesses antibacterial activity that can be further explored to produce new medicinal products.
format Article
author Najmuldeen, Ghazi Faisal
G. G., Faisal
S. M., Zakaria
author_facet Najmuldeen, Ghazi Faisal
G. G., Faisal
S. M., Zakaria
author_sort Najmuldeen, Ghazi Faisal
title In Vitro Antibacterial Activity of Eurycoma Longifolia Jack (Tongkat Ali) Root Extract
title_short In Vitro Antibacterial Activity of Eurycoma Longifolia Jack (Tongkat Ali) Root Extract
title_full In Vitro Antibacterial Activity of Eurycoma Longifolia Jack (Tongkat Ali) Root Extract
title_fullStr In Vitro Antibacterial Activity of Eurycoma Longifolia Jack (Tongkat Ali) Root Extract
title_full_unstemmed In Vitro Antibacterial Activity of Eurycoma Longifolia Jack (Tongkat Ali) Root Extract
title_sort in vitro antibacterial activity of eurycoma longifolia jack (tongkat ali) root extract
publishDate 2015
url http://umpir.ump.edu.my/id/eprint/9418/
http://umpir.ump.edu.my/id/eprint/9418/
http://umpir.ump.edu.my/id/eprint/9418/1/In%20Vitro%20Antibacterial%20Activity%20of%20Eurycoma%20Longifolia%20Jack%20%28Tongkat%20Ali%29%20Root%20Extract.pdf
first_indexed 2023-09-18T22:07:58Z
last_indexed 2023-09-18T22:07:58Z
_version_ 1777414836266729472

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