α-Glucosidase and α-amylase Inhibitory Constituents of Tinospora crispa: Isolation and Chemical Profile Confirmation by Ultra-high Performance Liquid Chromatography-quadrupole Time-of-flight/mass spectrometry
Tinospora crispa has been used in Malaysia to treat diabetes mellitus. We evaluated the effects of compounds isolated from T. crispa vines on the starch digestive enzymes, α-glucosidase and α-amylase. Borapetoside C was the most potent α-glucosidase inhibitor (IC50 = 0.0527 ± 0.008 mg/ml), followed...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
Elsevier Ltd
2015
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| Subjects: | |
| Online Access: | http://umpir.ump.edu.my/id/eprint/9262/ http://umpir.ump.edu.my/id/eprint/9262/ http://umpir.ump.edu.my/id/eprint/9262/ http://umpir.ump.edu.my/id/eprint/9262/1/fist-2015-mashitah- http://umpir.ump.edu.my/id/eprint/9262/2/a-Glucosidase%20and%20a-amylase%20Inhibitory%20constituents%20of%20Tinospora%20crispa-%20Isolation%20and%20Chemical%20Profile%20Confirmation%20by%20Ultra-High%20Performance%20Liquid%20Chromatography-Quadrupole%20Time-Of-Flight-Mass%20Spectrometry.pdf |