Synthesis of molecularly imprinted polymer for glucose binding

Molecularly imprinted polymer (MIP) is an attractive technique for the synthesis of highly selective polymeric receptors having artificial generated recognition sites. These materials were synthesized with polymerizable functional monomers and crosslinker that were surrounded around the template mol...

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Main Author:	Nurul Atiqah, Abdul Hamid
Format:	Undergraduates Project Papers
Language:	English
Published:	2014
Subjects:	TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/9232/ http://umpir.ump.edu.my/id/eprint/9232/ http://umpir.ump.edu.my/id/eprint/9232/1/cd8606.pdf

id	ump-9232
recordtype	eprints
spelling	ump-92322015-10-12T06:05:15Z http://umpir.ump.edu.my/id/eprint/9232/ Synthesis of molecularly imprinted polymer for glucose binding Nurul Atiqah, Abdul Hamid TP Chemical technology Molecularly imprinted polymer (MIP) is an attractive technique for the synthesis of highly selective polymeric receptors having artificial generated recognition sites. These materials were synthesized with polymerizable functional monomers and crosslinker that were surrounded around the template molecule. After polymerization, a template molecule was removed leaving in the polymer selective recognition sites with shape, size and functionalities complementary to the template. This study presents a synthesis of MIP selectively for glucose binding. Glucose phosphate salt (GPS) was used as a template molecule with poly(allylamine hydrochloride) (PAA.HCl) as a functional monomer. Three types of crosslinkers which are epichlorohydrin (EPI), ethylene glycol diglycidyl ether (EDGE) and glycerol diglycidyl ether (GDE) were studied during the MIP synthesis. MIP prepared using EPI as a crosslinking showed the highest glucose binding capacity around 0.84 mg glucose/mg dried gel. The binding capacity of MIP prepared using EGDE and GDE are 0.78 mg glucose/mg gel and 0.38 mg glucose/mg gel respectively. It is also found that the increase on GPS monomer concentration will contribute to increase in glucose binding 2014-01 Undergraduates Project Papers NonPeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/9232/1/cd8606.pdf Nurul Atiqah, Abdul Hamid (2014) Synthesis of molecularly imprinted polymer for glucose binding. Faculty of Chemical & Natural Resources Engineering, Universiti Malaysia Pahang. http://iportal.ump.edu.my/lib/item?id=chamo:84777&theme=UMP2
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	TP Chemical technology
spellingShingle	TP Chemical technology Nurul Atiqah, Abdul Hamid Synthesis of molecularly imprinted polymer for glucose binding
description	Molecularly imprinted polymer (MIP) is an attractive technique for the synthesis of highly selective polymeric receptors having artificial generated recognition sites. These materials were synthesized with polymerizable functional monomers and crosslinker that were surrounded around the template molecule. After polymerization, a template molecule was removed leaving in the polymer selective recognition sites with shape, size and functionalities complementary to the template. This study presents a synthesis of MIP selectively for glucose binding. Glucose phosphate salt (GPS) was used as a template molecule with poly(allylamine hydrochloride) (PAA.HCl) as a functional monomer. Three types of crosslinkers which are epichlorohydrin (EPI), ethylene glycol diglycidyl ether (EDGE) and glycerol diglycidyl ether (GDE) were studied during the MIP synthesis. MIP prepared using EPI as a crosslinking showed the highest glucose binding capacity around 0.84 mg glucose/mg dried gel. The binding capacity of MIP prepared using EGDE and GDE are 0.78 mg glucose/mg gel and 0.38 mg glucose/mg gel respectively. It is also found that the increase on GPS monomer concentration will contribute to increase in glucose binding
format	Undergraduates Project Papers
author	Nurul Atiqah, Abdul Hamid
author_facet	Nurul Atiqah, Abdul Hamid
author_sort	Nurul Atiqah, Abdul Hamid
title	Synthesis of molecularly imprinted polymer for glucose binding
title_short	Synthesis of molecularly imprinted polymer for glucose binding
title_full	Synthesis of molecularly imprinted polymer for glucose binding
title_fullStr	Synthesis of molecularly imprinted polymer for glucose binding
title_full_unstemmed	Synthesis of molecularly imprinted polymer for glucose binding
title_sort	synthesis of molecularly imprinted polymer for glucose binding
publishDate	2014
url	http://umpir.ump.edu.my/id/eprint/9232/ http://umpir.ump.edu.my/id/eprint/9232/ http://umpir.ump.edu.my/id/eprint/9232/1/cd8606.pdf
first_indexed	2023-09-18T22:07:35Z
last_indexed	2023-09-18T22:07:35Z
_version_	1777414812187230208

Synthesis of molecularly imprinted polymer for glucose binding

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