Oral Bacteria: Antimicrobial and Virulence

Tooth decay is considered the most widespread infectious disease in the world. Its spread increases with time, and this increase is associated significantly with the change of dietary mode of modern humans. This study aims to isolate and identify the important bacteria related to tooth decay, dete...

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Main Authors: Ali, Muna Jalal, Makky, Essam A., M. M., Yusoff
Format: Article
Language:English
Published: JOCPR 2015
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/8965/
http://umpir.ump.edu.my/id/eprint/8965/
http://umpir.ump.edu.my/id/eprint/8965/1/Oral%20bacteria-%20Antimicrobial%20and%20virulence.pdf
id ump-8965
recordtype eprints
spelling ump-89652018-07-26T03:32:08Z http://umpir.ump.edu.my/id/eprint/8965/ Oral Bacteria: Antimicrobial and Virulence Ali, Muna Jalal Makky, Essam A. M. M., Yusoff Q Science (General) Tooth decay is considered the most widespread infectious disease in the world. Its spread increases with time, and this increase is associated significantly with the change of dietary mode of modern humans. This study aims to isolate and identify the important bacteria related to tooth decay, determine the sensitivity of bacteria in certain types of antimicrobial agents, and study the effect of heavy metals on bacterial isolates. A total of 50 swabs were collected from the mouths of patients from both sexes, with ages ranging from 1–60 years. The patients were advised to consult with dental clinics and specialized centers to isolate and identify the causative agents associated with oral diseases. Results showed that infection rates in younger age groups (1–20 and 20–40) are higher than the elder group (40–60), with percent incidence of 44% and 32%, respectively. Antibiotic sensitivity test against the isolates showed that chloramphenicol had the highest sensitivity effect with 83.2% followed by rifampicin and gentamicin with 81.35%, penicillin G with 64.40%, and streptomycin with 16.94%. In addition, hemolysin had the highest ability to produce virulence factors (72.88%), followed by lecithinase (42.37%) and protease (25.42%). Lipase and urease had the lowest virulence factor production (10.16%). JOCPR 2015 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/8965/1/Oral%20bacteria-%20Antimicrobial%20and%20virulence.pdf Ali, Muna Jalal and Makky, Essam A. and M. M., Yusoff (2015) Oral Bacteria: Antimicrobial and Virulence. Journal of Chemical and Pharmaceutical Research, 7 (3). pp. 1816-1821. ISSN 0975-7384 http://jocpr.com/vol7-iss3-2015/JCPR-2015-7-3-1816-1821.pdf
repository_type Digital Repository
institution_category Local University
institution Universiti Malaysia Pahang
building UMP Institutional Repository
collection Online Access
language English
topic Q Science (General)
spellingShingle Q Science (General)
Ali, Muna Jalal
Makky, Essam A.
M. M., Yusoff
Oral Bacteria: Antimicrobial and Virulence
description Tooth decay is considered the most widespread infectious disease in the world. Its spread increases with time, and this increase is associated significantly with the change of dietary mode of modern humans. This study aims to isolate and identify the important bacteria related to tooth decay, determine the sensitivity of bacteria in certain types of antimicrobial agents, and study the effect of heavy metals on bacterial isolates. A total of 50 swabs were collected from the mouths of patients from both sexes, with ages ranging from 1–60 years. The patients were advised to consult with dental clinics and specialized centers to isolate and identify the causative agents associated with oral diseases. Results showed that infection rates in younger age groups (1–20 and 20–40) are higher than the elder group (40–60), with percent incidence of 44% and 32%, respectively. Antibiotic sensitivity test against the isolates showed that chloramphenicol had the highest sensitivity effect with 83.2% followed by rifampicin and gentamicin with 81.35%, penicillin G with 64.40%, and streptomycin with 16.94%. In addition, hemolysin had the highest ability to produce virulence factors (72.88%), followed by lecithinase (42.37%) and protease (25.42%). Lipase and urease had the lowest virulence factor production (10.16%).
format Article
author Ali, Muna Jalal
Makky, Essam A.
M. M., Yusoff
author_facet Ali, Muna Jalal
Makky, Essam A.
M. M., Yusoff
author_sort Ali, Muna Jalal
title Oral Bacteria: Antimicrobial and Virulence
title_short Oral Bacteria: Antimicrobial and Virulence
title_full Oral Bacteria: Antimicrobial and Virulence
title_fullStr Oral Bacteria: Antimicrobial and Virulence
title_full_unstemmed Oral Bacteria: Antimicrobial and Virulence
title_sort oral bacteria: antimicrobial and virulence
publisher JOCPR
publishDate 2015
url http://umpir.ump.edu.my/id/eprint/8965/
http://umpir.ump.edu.my/id/eprint/8965/
http://umpir.ump.edu.my/id/eprint/8965/1/Oral%20bacteria-%20Antimicrobial%20and%20virulence.pdf
first_indexed 2023-09-18T22:07:00Z
last_indexed 2023-09-18T22:07:00Z
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