Antibacterial activities of extracts from different parts of Swietenia mahagoni against multiple-drug resistant bacteria

This study concerned with the evaluation of antibacterial activity of crude extracts of three parts (leaf, fruit cover, seed cover and seed) of Swietenia mahagoni obtained by three solvents (acetone, ethanol and hexane). The seedoil obtained by solvent continuous extraction method (Soxhiet) from see...

Full description

Bibliographic Details
Main Author:	Tan, Wee Yeong
Format:	Undergraduates Project Papers
Language:	English
Published:	2012
Subjects:	QR Microbiology
Online Access:	http://umpir.ump.edu.my/id/eprint/7846/ http://umpir.ump.edu.my/id/eprint/7846/ http://umpir.ump.edu.my/id/eprint/7846/1/TAN_WEE_YEONG.PDF

id	ump-7846
recordtype	eprints
spelling	ump-78462015-03-03T09:38:25Z http://umpir.ump.edu.my/id/eprint/7846/ Antibacterial activities of extracts from different parts of Swietenia mahagoni against multiple-drug resistant bacteria Tan, Wee Yeong QR Microbiology This study concerned with the evaluation of antibacterial activity of crude extracts of three parts (leaf, fruit cover, seed cover and seed) of Swietenia mahagoni obtained by three solvents (acetone, ethanol and hexane). The seedoil obtained by solvent continuous extraction method (Soxhiet) from seed by using hexane as solvent. The antibacterial activity of these extracts was assessed against two multiple-drug-resistance bacteria strains namely, Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) by the well diffusion method. For the antibacterial bioassay, four concentrations (0.1, 0.2, 0.4 and 0.8%) of each solvent and part extract solutions were prepared; DMSO was used to solubilize the extract in water. A control using 1% dimethyl suldoxide (DMSO) used for comparison. The antibacterial activity among extracts was extremely broad against both test organisms. With higher concentration (0.8%) the acetone extracts from fruit cover and leaf displayed overall more potent activity than other parts against S. aureus; whereas ethanol extracts from fruit and seed cover showed more efficiency against E. coli. However, no inhibition activity of leaf acetone and ethanol against E. coli with concentration of 0.8%. Bioactive groups such as alkaloid and sesquiterpene lactones were screened by Thin Layer Chromatography (TLC); and the results obtained were positive. The experimental results obtained from this study suggest that Swietenia mahagoni extracts are promising as natural antibacterial and this may warrant further research to determine the bioactive compound(s). 2012 Undergraduates Project Papers NonPeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/7846/1/TAN_WEE_YEONG.PDF Tan, Wee Yeong (2012) Antibacterial activities of extracts from different parts of Swietenia mahagoni against multiple-drug resistant bacteria. Faculty of Industrial Sciences & Technology, Universiti Malaysia Pahang. http://iportal.ump.edu.my/lib/item?id=chamo:76310&theme=UMP2
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	QR Microbiology
spellingShingle	QR Microbiology Tan, Wee Yeong Antibacterial activities of extracts from different parts of Swietenia mahagoni against multiple-drug resistant bacteria
description	This study concerned with the evaluation of antibacterial activity of crude extracts of three parts (leaf, fruit cover, seed cover and seed) of Swietenia mahagoni obtained by three solvents (acetone, ethanol and hexane). The seedoil obtained by solvent continuous extraction method (Soxhiet) from seed by using hexane as solvent. The antibacterial activity of these extracts was assessed against two multiple-drug-resistance bacteria strains namely, Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) by the well diffusion method. For the antibacterial bioassay, four concentrations (0.1, 0.2, 0.4 and 0.8%) of each solvent and part extract solutions were prepared; DMSO was used to solubilize the extract in water. A control using 1% dimethyl suldoxide (DMSO) used for comparison. The antibacterial activity among extracts was extremely broad against both test organisms. With higher concentration (0.8%) the acetone extracts from fruit cover and leaf displayed overall more potent activity than other parts against S. aureus; whereas ethanol extracts from fruit and seed cover showed more efficiency against E. coli. However, no inhibition activity of leaf acetone and ethanol against E. coli with concentration of 0.8%. Bioactive groups such as alkaloid and sesquiterpene lactones were screened by Thin Layer Chromatography (TLC); and the results obtained were positive. The experimental results obtained from this study suggest that Swietenia mahagoni extracts are promising as natural antibacterial and this may warrant further research to determine the bioactive compound(s).
format	Undergraduates Project Papers
author	Tan, Wee Yeong
author_facet	Tan, Wee Yeong
author_sort	Tan, Wee Yeong
title	Antibacterial activities of extracts from different parts of Swietenia mahagoni against multiple-drug resistant bacteria
title_short	Antibacterial activities of extracts from different parts of Swietenia mahagoni against multiple-drug resistant bacteria
title_full	Antibacterial activities of extracts from different parts of Swietenia mahagoni against multiple-drug resistant bacteria
title_fullStr	Antibacterial activities of extracts from different parts of Swietenia mahagoni against multiple-drug resistant bacteria
title_full_unstemmed	Antibacterial activities of extracts from different parts of Swietenia mahagoni against multiple-drug resistant bacteria
title_sort	antibacterial activities of extracts from different parts of swietenia mahagoni against multiple-drug resistant bacteria
publishDate	2012
url	http://umpir.ump.edu.my/id/eprint/7846/ http://umpir.ump.edu.my/id/eprint/7846/ http://umpir.ump.edu.my/id/eprint/7846/1/TAN_WEE_YEONG.PDF
first_indexed	2023-09-18T22:04:54Z
last_indexed	2023-09-18T22:04:54Z
_version_	1777414642954403840

Antibacterial activities of extracts from different parts of Swietenia mahagoni against multiple-drug resistant bacteria

Similar Items