Coaxial Electrospun Nanofibers as Pharmaceutical Nanoformulation for Controlled Drug Release

Pharmaceutical nanoformulations for controlled drug release, caters to the need of targeted delivery thereby minimizing the side effects and the economics of the drug regimen costing. Electrospinning produces nanofibers which has enormous application for diversified usage in healthcare, green techno...

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Main Authors:	Amiruddin, Fadzli Zaini, Balu, Ranganathan, Subramaniam , Sundarrajan, Seeram , Ramakrishna
Format:	Conference or Workshop Item
Language:	English
Published:	2014
Subjects:	TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/7599/ http://umpir.ump.edu.my/id/eprint/7599/ http://umpir.ump.edu.my/id/eprint/7599/1/Coaxial_electrospun_nanofibers_as_pharmaceutical_nanoformulation_for_controlled_drug_release.pdf

id	ump-7599
recordtype	eprints
spelling	ump-75992015-03-03T09:37:00Z http://umpir.ump.edu.my/id/eprint/7599/ Coaxial Electrospun Nanofibers as Pharmaceutical Nanoformulation for Controlled Drug Release Amiruddin, Fadzli Zaini Balu, Ranganathan Subramaniam , Sundarrajan Seeram , Ramakrishna TP Chemical technology Pharmaceutical nanoformulations for controlled drug release, caters to the need of targeted delivery thereby minimizing the side effects and the economics of the drug regimen costing. Electrospinning produces nanofibers which has enormous application for diversified usage in healthcare, green technology, filtration and military aids. Organic polymeric nanofibers are used for healthcare applications. FDA approved organic polymers, PCL, PLLA and block copolymer PLLA-CL were used for the fabrication of nanofibers for controlled drug release. Coaxial nanofibers were produced with protein molecules embedded in the core structure and FDA approved organic polymer in the shell structure protecting the highly labile protein molecules from denaturation. Bovine Serum Albumin (BSA), Lysozyme and IgG are the protein mixture embedded in the core structure. Different concentrations of polymeric material of PCL, PLLA and block copolymer PLLA-CL were used in the range of 10–18% (W/V). The solvents used were highly evaporable with approved residual levels presence in the nanofibers scaffolds. 2014 Conference or Workshop Item PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/7599/1/Coaxial_electrospun_nanofibers_as_pharmaceutical_nanoformulation_for_controlled_drug_release.pdf Amiruddin, Fadzli Zaini and Balu, Ranganathan and Subramaniam , Sundarrajan and Seeram , Ramakrishna (2014) Coaxial Electrospun Nanofibers as Pharmaceutical Nanoformulation for Controlled Drug Release. In: 14th International Conference on Nanotechnology (IEEE-NANO), 18-21 Aug. 2014 , Toronto, ON, Canada. pp. 531-534.. http://dx.doi.org/10.1109/NANO.2014.6968190
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	TP Chemical technology
spellingShingle	TP Chemical technology Amiruddin, Fadzli Zaini Balu, Ranganathan Subramaniam , Sundarrajan Seeram , Ramakrishna Coaxial Electrospun Nanofibers as Pharmaceutical Nanoformulation for Controlled Drug Release
description	Pharmaceutical nanoformulations for controlled drug release, caters to the need of targeted delivery thereby minimizing the side effects and the economics of the drug regimen costing. Electrospinning produces nanofibers which has enormous application for diversified usage in healthcare, green technology, filtration and military aids. Organic polymeric nanofibers are used for healthcare applications. FDA approved organic polymers, PCL, PLLA and block copolymer PLLA-CL were used for the fabrication of nanofibers for controlled drug release. Coaxial nanofibers were produced with protein molecules embedded in the core structure and FDA approved organic polymer in the shell structure protecting the highly labile protein molecules from denaturation. Bovine Serum Albumin (BSA), Lysozyme and IgG are the protein mixture embedded in the core structure. Different concentrations of polymeric material of PCL, PLLA and block copolymer PLLA-CL were used in the range of 10–18% (W/V). The solvents used were highly evaporable with approved residual levels presence in the nanofibers scaffolds.
format	Conference or Workshop Item
author	Amiruddin, Fadzli Zaini Balu, Ranganathan Subramaniam , Sundarrajan Seeram , Ramakrishna
author_facet	Amiruddin, Fadzli Zaini Balu, Ranganathan Subramaniam , Sundarrajan Seeram , Ramakrishna
author_sort	Amiruddin, Fadzli Zaini
title	Coaxial Electrospun Nanofibers as Pharmaceutical Nanoformulation for Controlled Drug Release
title_short	Coaxial Electrospun Nanofibers as Pharmaceutical Nanoformulation for Controlled Drug Release
title_full	Coaxial Electrospun Nanofibers as Pharmaceutical Nanoformulation for Controlled Drug Release
title_fullStr	Coaxial Electrospun Nanofibers as Pharmaceutical Nanoformulation for Controlled Drug Release
title_full_unstemmed	Coaxial Electrospun Nanofibers as Pharmaceutical Nanoformulation for Controlled Drug Release
title_sort	coaxial electrospun nanofibers as pharmaceutical nanoformulation for controlled drug release
publishDate	2014
url	http://umpir.ump.edu.my/id/eprint/7599/ http://umpir.ump.edu.my/id/eprint/7599/ http://umpir.ump.edu.my/id/eprint/7599/1/Coaxial_electrospun_nanofibers_as_pharmaceutical_nanoformulation_for_controlled_drug_release.pdf
first_indexed	2023-09-18T22:04:22Z
last_indexed	2023-09-18T22:04:22Z
_version_	1777414609026678784

Coaxial Electrospun Nanofibers as Pharmaceutical Nanoformulation for Controlled Drug Release

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