Molecular Dynamics Simulation of Ibuprofen Crystal Polymorph

Ibuprofen (iso-butyl-propanolic acid) is one of the Active Pharmaceutical Ingredients (API) that uses to treat a symptom of rheumatism, arthritis, fever, as an analgesic (pain reliever). This study aims to identify which solvents should affect the polymorph of ibuprofen begins from the crystallizati...

Full description

Bibliographic Details
Main Author:	Mohammad Safuan, Mat Noor
Format:	Undergraduates Project Papers
Language:	English
Published:	2012
Subjects:	QD Chemistry
Online Access:	http://umpir.ump.edu.my/id/eprint/7221/ http://umpir.ump.edu.my/id/eprint/7221/ http://umpir.ump.edu.my/id/eprint/7221/1/CD7091.pdf

id	ump-7221
recordtype	eprints
spelling	ump-72212015-03-03T09:34:50Z http://umpir.ump.edu.my/id/eprint/7221/ Molecular Dynamics Simulation of Ibuprofen Crystal Polymorph Mohammad Safuan, Mat Noor QD Chemistry Ibuprofen (iso-butyl-propanolic acid) is one of the Active Pharmaceutical Ingredients (API) that uses to treat a symptom of rheumatism, arthritis, fever, as an analgesic (pain reliever). This study aims to identify which solvents should affect the polymorph of ibuprofen begins from the crystallization solution. The Molecular Dynamics Simulation and Fourier transform infrared (FTIR) is used to recognize which molecules that form hydrogen bond in the ibuprofen crystal polymorph. The study analysis has shown that the higher hydrogen bond between the atoms will contribute to the ibuprofen crystal polymorph. As the conclusion, only the selected atoms will contribute in the formation of desired crystal polymorph of ibuprofen. 2012-02 Undergraduates Project Papers NonPeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/7221/1/CD7091.pdf Mohammad Safuan, Mat Noor (2012) Molecular Dynamics Simulation of Ibuprofen Crystal Polymorph. Faculty of Chemical and Natural Resources Engineering, Universiti Malaysia Pahang. http://iportal.ump.edu.my/lib/item?id=chamo:75879&theme=UMP2
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	QD Chemistry
spellingShingle	QD Chemistry Mohammad Safuan, Mat Noor Molecular Dynamics Simulation of Ibuprofen Crystal Polymorph
description	Ibuprofen (iso-butyl-propanolic acid) is one of the Active Pharmaceutical Ingredients (API) that uses to treat a symptom of rheumatism, arthritis, fever, as an analgesic (pain reliever). This study aims to identify which solvents should affect the polymorph of ibuprofen begins from the crystallization solution. The Molecular Dynamics Simulation and Fourier transform infrared (FTIR) is used to recognize which molecules that form hydrogen bond in the ibuprofen crystal polymorph. The study analysis has shown that the higher hydrogen bond between the atoms will contribute to the ibuprofen crystal polymorph. As the conclusion, only the selected atoms will contribute in the formation of desired crystal polymorph of ibuprofen.
format	Undergraduates Project Papers
author	Mohammad Safuan, Mat Noor
author_facet	Mohammad Safuan, Mat Noor
author_sort	Mohammad Safuan, Mat Noor
title	Molecular Dynamics Simulation of Ibuprofen Crystal Polymorph
title_short	Molecular Dynamics Simulation of Ibuprofen Crystal Polymorph
title_full	Molecular Dynamics Simulation of Ibuprofen Crystal Polymorph
title_fullStr	Molecular Dynamics Simulation of Ibuprofen Crystal Polymorph
title_full_unstemmed	Molecular Dynamics Simulation of Ibuprofen Crystal Polymorph
title_sort	molecular dynamics simulation of ibuprofen crystal polymorph
publishDate	2012
url	http://umpir.ump.edu.my/id/eprint/7221/ http://umpir.ump.edu.my/id/eprint/7221/ http://umpir.ump.edu.my/id/eprint/7221/1/CD7091.pdf
first_indexed	2023-09-18T22:03:44Z
last_indexed	2023-09-18T22:03:44Z
_version_	1777414569418817536

Molecular Dynamics Simulation of Ibuprofen Crystal Polymorph

Similar Items