Qualitative Measurement of Pain by Analysing the Salivary Alpha Amylase

The purpose of the study was to develop a qualitative measurement for pain by measuring salivary alpha amylase (sAA). In this study, sAA levels were measured in order to investigate the relativity between fluctuation of sAA and pain on Institute of Cancer Research (ICR) mice by injection needle as a...

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Main Authors:	Mohd Yusri, Saidin, Tsuchiya, Kazuyoshi, Inoue, Takehiko, Kajiwara, Kagemasa, Kimura, Minoru
Format:	Article
Language:	English
Published:	Elsevier 2014
Subjects:	TJ Mechanical engineering and machinery
Online Access:	http://umpir.ump.edu.my/id/eprint/5820/ http://umpir.ump.edu.my/id/eprint/5820/ http://umpir.ump.edu.my/id/eprint/5820/ http://umpir.ump.edu.my/id/eprint/5820/1/fkm-2014-yusri-qualitative_measurement_abs_only.pdf

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recordtype	eprints
spelling	ump-58202015-03-03T09:26:44Z http://umpir.ump.edu.my/id/eprint/5820/ Qualitative Measurement of Pain by Analysing the Salivary Alpha Amylase Mohd Yusri, Saidin Tsuchiya, Kazuyoshi Inoue, Takehiko Kajiwara, Kagemasa Kimura, Minoru TJ Mechanical engineering and machinery The purpose of the study was to develop a qualitative measurement for pain by measuring salivary alpha amylase (sAA). In this study, sAA levels were measured in order to investigate the relativity between fluctuation of sAA and pain on Institute of Cancer Research (ICR) mice by injection needle as a physical stimulus. Mice were chosen as an object of experiment since mice and human have similarities in both physical behaviour and biological behaviour. Here, ICR mice were divided into two groups; injected by Nanopass 33 (TERUMO Corporation, 100 μm and 200 μm in inner and outer diameter) and a control (without any injection). Whole saliva was collected from the oral cavity by micropipette for both groups. As a result, there was a significant difference in sAA levels between the two groups as the p value (probability value) was below than 0.01 (p < 0.01). Therefore, this is the first study showing the non-invasive method of qualitative pain measurement for minor damage caused by physical stimulus. The results demonstrate the potential of sAA as an indirect marker for pain and suggest that the present experimental situation is a suitable experimental model for measuring pain. Elsevier 2014-04 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/5820/1/fkm-2014-yusri-qualitative_measurement_abs_only.pdf Mohd Yusri, Saidin and Tsuchiya, Kazuyoshi and Inoue, Takehiko and Kajiwara, Kagemasa and Kimura, Minoru (2014) Qualitative Measurement of Pain by Analysing the Salivary Alpha Amylase. Precision Engineering, 38 (2). 257-260 . ISSN 0141-6359 http://dx.doi.org/10.1016/j.precisioneng.2013.09.006 DOI: 10.1016/j.precisioneng.2013.09.006
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	TJ Mechanical engineering and machinery
spellingShingle	TJ Mechanical engineering and machinery Mohd Yusri, Saidin Tsuchiya, Kazuyoshi Inoue, Takehiko Kajiwara, Kagemasa Kimura, Minoru Qualitative Measurement of Pain by Analysing the Salivary Alpha Amylase
description	The purpose of the study was to develop a qualitative measurement for pain by measuring salivary alpha amylase (sAA). In this study, sAA levels were measured in order to investigate the relativity between fluctuation of sAA and pain on Institute of Cancer Research (ICR) mice by injection needle as a physical stimulus. Mice were chosen as an object of experiment since mice and human have similarities in both physical behaviour and biological behaviour. Here, ICR mice were divided into two groups; injected by Nanopass 33 (TERUMO Corporation, 100 μm and 200 μm in inner and outer diameter) and a control (without any injection). Whole saliva was collected from the oral cavity by micropipette for both groups. As a result, there was a significant difference in sAA levels between the two groups as the p value (probability value) was below than 0.01 (p < 0.01). Therefore, this is the first study showing the non-invasive method of qualitative pain measurement for minor damage caused by physical stimulus. The results demonstrate the potential of sAA as an indirect marker for pain and suggest that the present experimental situation is a suitable experimental model for measuring pain.
format	Article
author	Mohd Yusri, Saidin Tsuchiya, Kazuyoshi Inoue, Takehiko Kajiwara, Kagemasa Kimura, Minoru
author_facet	Mohd Yusri, Saidin Tsuchiya, Kazuyoshi Inoue, Takehiko Kajiwara, Kagemasa Kimura, Minoru
author_sort	Mohd Yusri, Saidin
title	Qualitative Measurement of Pain by Analysing the Salivary Alpha Amylase
title_short	Qualitative Measurement of Pain by Analysing the Salivary Alpha Amylase
title_full	Qualitative Measurement of Pain by Analysing the Salivary Alpha Amylase
title_fullStr	Qualitative Measurement of Pain by Analysing the Salivary Alpha Amylase
title_full_unstemmed	Qualitative Measurement of Pain by Analysing the Salivary Alpha Amylase
title_sort	qualitative measurement of pain by analysing the salivary alpha amylase
publisher	Elsevier
publishDate	2014
url	http://umpir.ump.edu.my/id/eprint/5820/ http://umpir.ump.edu.my/id/eprint/5820/ http://umpir.ump.edu.my/id/eprint/5820/ http://umpir.ump.edu.my/id/eprint/5820/1/fkm-2014-yusri-qualitative_measurement_abs_only.pdf
first_indexed	2023-09-18T22:01:14Z
last_indexed	2023-09-18T22:01:14Z
_version_	1777414411841961984

Qualitative Measurement of Pain by Analysing the Salivary Alpha Amylase

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