Scaffolds from Chemically Modified Cellulose Nanofibers for Skin Tissue Engineering

The objective of this research is to develop a three-dimensional porous scaffold to support cell adhesion and proliferation and to guide cells moving into the repair area in the wound healing process by using electrospinning technique. A series of modified cellulose/PVA nanofibers scaffolds in diffe...

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Main Authors:	Farah Hanani, Zulkifli, Jahir Hussain, Fathima Shahitha, M. M., Yusoff, Chahal, Sugandha
Format:	Conference or Workshop Item
Language:	English
Published:	2013
Subjects:	QD Chemistry
Online Access:	http://umpir.ump.edu.my/id/eprint/5790/ http://umpir.ump.edu.my/id/eprint/5790/1/SCI-017.pdf

id	ump-5790
recordtype	eprints
spelling	ump-57902018-07-26T06:56:47Z http://umpir.ump.edu.my/id/eprint/5790/ Scaffolds from Chemically Modified Cellulose Nanofibers for Skin Tissue Engineering Farah Hanani, Zulkifli Jahir Hussain, Fathima Shahitha M. M., Yusoff Chahal, Sugandha QD Chemistry The objective of this research is to develop a three-dimensional porous scaffold to support cell adhesion and proliferation and to guide cells moving into the repair area in the wound healing process by using electrospinning technique. A series of modified cellulose/PVA nanofibers scaffolds in different concentrations were prepared and blended to evaluate the optimal tissue engineering scaffold. The cross-linking nanofibers scaffolds were characterized by scanning electron microscope(SEM), Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). SEM images revealed that with decreasing cellulose content the average diameters of blend nanofibers were increased from 241±17.03 to 320±27.17 nm. Biocompatibility assay showed cells attached and spread actively on all modified cellulose nanofibers scaffolds with globular morphology after 7 days culturing which exhibit excellent biocompatibility and enhancement of cell penetration and growth within nanofibers mats. Results indicate that the modified cellulose have potential application in skin tissue engineering. 2013 Conference or Workshop Item PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/5790/1/SCI-017.pdf Farah Hanani, Zulkifli and Jahir Hussain, Fathima Shahitha and M. M., Yusoff and Chahal, Sugandha (2013) Scaffolds from Chemically Modified Cellulose Nanofibers for Skin Tissue Engineering. In: Malaysian Technical Universities Conference on Engineering & Technology (MUCET 2013), 3-4 December 2013 , Kuantan, Pahang. p. 1..
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	QD Chemistry
spellingShingle	QD Chemistry Farah Hanani, Zulkifli Jahir Hussain, Fathima Shahitha M. M., Yusoff Chahal, Sugandha Scaffolds from Chemically Modified Cellulose Nanofibers for Skin Tissue Engineering
description	The objective of this research is to develop a three-dimensional porous scaffold to support cell adhesion and proliferation and to guide cells moving into the repair area in the wound healing process by using electrospinning technique. A series of modified cellulose/PVA nanofibers scaffolds in different concentrations were prepared and blended to evaluate the optimal tissue engineering scaffold. The cross-linking nanofibers scaffolds were characterized by scanning electron microscope(SEM), Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). SEM images revealed that with decreasing cellulose content the average diameters of blend nanofibers were increased from 241±17.03 to 320±27.17 nm. Biocompatibility assay showed cells attached and spread actively on all modified cellulose nanofibers scaffolds with globular morphology after 7 days culturing which exhibit excellent biocompatibility and enhancement of cell penetration and growth within nanofibers mats. Results indicate that the modified cellulose have potential application in skin tissue engineering.
format	Conference or Workshop Item
author	Farah Hanani, Zulkifli Jahir Hussain, Fathima Shahitha M. M., Yusoff Chahal, Sugandha
author_facet	Farah Hanani, Zulkifli Jahir Hussain, Fathima Shahitha M. M., Yusoff Chahal, Sugandha
author_sort	Farah Hanani, Zulkifli
title	Scaffolds from Chemically Modified Cellulose Nanofibers for Skin Tissue Engineering
title_short	Scaffolds from Chemically Modified Cellulose Nanofibers for Skin Tissue Engineering
title_full	Scaffolds from Chemically Modified Cellulose Nanofibers for Skin Tissue Engineering
title_fullStr	Scaffolds from Chemically Modified Cellulose Nanofibers for Skin Tissue Engineering
title_full_unstemmed	Scaffolds from Chemically Modified Cellulose Nanofibers for Skin Tissue Engineering
title_sort	scaffolds from chemically modified cellulose nanofibers for skin tissue engineering
publishDate	2013
url	http://umpir.ump.edu.my/id/eprint/5790/ http://umpir.ump.edu.my/id/eprint/5790/1/SCI-017.pdf
first_indexed	2023-09-18T22:01:11Z
last_indexed	2023-09-18T22:01:11Z
_version_	1777414408765440000

Scaffolds from Chemically Modified Cellulose Nanofibers for Skin Tissue Engineering

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