Optimization of encapsulation of natural dye by cyclodextrin using response surface methodology

Nowadays,cyclodextrin widely used in industries due to its ability in encapsulation process with natural dye. However, the production cost for cyclodextrin is very expensive.A study on how to reduce the production cost by optimization of pH, concentration of cyclodextrin and temperature effect on en...

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Main Author:	Nor Ashikin , Abdul Hamid
Format:	Undergraduates Project Papers
Language:	English
Published:	2010
Subjects:	TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/5353/ http://umpir.ump.edu.my/id/eprint/5353/ http://umpir.ump.edu.my/id/eprint/5353/1/CD5870.pdf

id	ump-5353
recordtype	eprints
spelling	ump-53532015-03-03T09:24:24Z http://umpir.ump.edu.my/id/eprint/5353/ Optimization of encapsulation of natural dye by cyclodextrin using response surface methodology Nor Ashikin , Abdul Hamid TP Chemical technology Nowadays,cyclodextrin widely used in industries due to its ability in encapsulation process with natural dye. However, the production cost for cyclodextrin is very expensive.A study on how to reduce the production cost by optimization of pH, concentration of cyclodextrin and temperature effect on encapsulation of natural dye by cyclodextrin using Response Surface Methodology(RSM)was successfully done. During the preliminary experiment,one factor at a time was employed to screen the best range for pH,concentration of cyclodextrin and temperature.All the parameter ranges obtained were used in RSM.RSM software in Design Expert version 6.0.8 was used with Central Composite Design(CCD) mode.Seventeen sets of experiments with different parameter values were suggested by the software.The predicted optimum values for pH,concentration of cyclodextrin,temperature and concentration of encapsulation of natural dye-β-cyclodextrin were pH 3.11,0.004 mol/L,60 oC and 1.27763 g/L respectively.One set of experiment was run using the optimized parameter and as a result,1.2534 g/L concentration on encapsulation of natural dye-β-cyclodextrin was recorded. Before optimization, concentration on encapsulation of natural dye-β-cyclodextrin was only 0.775 g/L and the concentration was increased by 38.17% after optimization. The optimization also reduces the cost and energy consumption as the pH reduced from pH 10.5 to pH 3.11, concentration of cyclodextrin reduced from 0.005 mol/L to 0.004 mol/L and temperature was reduced from 70 oC to 60 oC. As a conclusion, this study was successful to increase encapsulation of natural dye by cyclodextrin production, reduce the energy consumption and also be able to reduce the production cost of cyclodextrin. 2010-05 Undergraduates Project Papers NonPeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/5353/1/CD5870.pdf Nor Ashikin , Abdul Hamid (2010) Optimization of encapsulation of natural dye by cyclodextrin using response surface methodology. Faculty of Chemical & Natural Resource Engineering, Universiti Malaysia Pahang. http://iportal.ump.edu.my/lib/item?id=chamo:58583&theme=UMP2
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	TP Chemical technology
spellingShingle	TP Chemical technology Nor Ashikin , Abdul Hamid Optimization of encapsulation of natural dye by cyclodextrin using response surface methodology
description	Nowadays,cyclodextrin widely used in industries due to its ability in encapsulation process with natural dye. However, the production cost for cyclodextrin is very expensive.A study on how to reduce the production cost by optimization of pH, concentration of cyclodextrin and temperature effect on encapsulation of natural dye by cyclodextrin using Response Surface Methodology(RSM)was successfully done. During the preliminary experiment,one factor at a time was employed to screen the best range for pH,concentration of cyclodextrin and temperature.All the parameter ranges obtained were used in RSM.RSM software in Design Expert version 6.0.8 was used with Central Composite Design(CCD) mode.Seventeen sets of experiments with different parameter values were suggested by the software.The predicted optimum values for pH,concentration of cyclodextrin,temperature and concentration of encapsulation of natural dye-β-cyclodextrin were pH 3.11,0.004 mol/L,60 oC and 1.27763 g/L respectively.One set of experiment was run using the optimized parameter and as a result,1.2534 g/L concentration on encapsulation of natural dye-β-cyclodextrin was recorded. Before optimization, concentration on encapsulation of natural dye-β-cyclodextrin was only 0.775 g/L and the concentration was increased by 38.17% after optimization. The optimization also reduces the cost and energy consumption as the pH reduced from pH 10.5 to pH 3.11, concentration of cyclodextrin reduced from 0.005 mol/L to 0.004 mol/L and temperature was reduced from 70 oC to 60 oC. As a conclusion, this study was successful to increase encapsulation of natural dye by cyclodextrin production, reduce the energy consumption and also be able to reduce the production cost of cyclodextrin.
format	Undergraduates Project Papers
author	Nor Ashikin , Abdul Hamid
author_facet	Nor Ashikin , Abdul Hamid
author_sort	Nor Ashikin , Abdul Hamid
title	Optimization of encapsulation of natural dye by cyclodextrin using response surface methodology
title_short	Optimization of encapsulation of natural dye by cyclodextrin using response surface methodology
title_full	Optimization of encapsulation of natural dye by cyclodextrin using response surface methodology
title_fullStr	Optimization of encapsulation of natural dye by cyclodextrin using response surface methodology
title_full_unstemmed	Optimization of encapsulation of natural dye by cyclodextrin using response surface methodology
title_sort	optimization of encapsulation of natural dye by cyclodextrin using response surface methodology
publishDate	2010
url	http://umpir.ump.edu.my/id/eprint/5353/ http://umpir.ump.edu.my/id/eprint/5353/ http://umpir.ump.edu.my/id/eprint/5353/1/CD5870.pdf
first_indexed	2023-09-18T22:00:40Z
last_indexed	2023-09-18T22:00:40Z
_version_	1777414376288944128

Optimization of encapsulation of natural dye by cyclodextrin using response surface methodology

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