Fatty Acid Composition and Antibacterial Activity of Swietenia Macrophylla King Seed Oil

Pathogenic bacteria cause many acute and serious diseases, especially ‘multiple-drug-resistant’ strains have become such a problem due to overuse of antibiotics. Various medicinal plants are used to prevent or cure infectious diseases. The aims of this study were to determine the oil content, fatty...

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Main Authors:	M. M., Yusoff, Muhammed, B. Suliman, Nour, A. H., Azhari, H. Nour, Kuppusamy, Palaniselvam, A. R., Yuvaraj, Adam, Mazza S.
Format:	Article
Language:	English
Published:	Academic Journals 2013
Subjects:	Q Science (General) QD Chemistry
Online Access:	http://umpir.ump.edu.my/id/eprint/4700/ http://umpir.ump.edu.my/id/eprint/4700/ http://umpir.ump.edu.my/id/eprint/4700/ http://umpir.ump.edu.my/id/eprint/4700/1/Fatty_acid_composition_and_antibacterial_activity_of_Swietenia_Macrophylla_king_seed_oil.pdf

id	ump-4700
recordtype	eprints
spelling	ump-47002018-07-13T02:18:08Z http://umpir.ump.edu.my/id/eprint/4700/ Fatty Acid Composition and Antibacterial Activity of Swietenia Macrophylla King Seed Oil M. M., Yusoff Muhammed, B. Suliman Nour, A. H. Azhari, H. Nour Kuppusamy, Palaniselvam A. R., Yuvaraj Adam, Mazza S. Q Science (General) QD Chemistry Pathogenic bacteria cause many acute and serious diseases, especially ‘multiple-drug-resistant’ strains have become such a problem due to overuse of antibiotics. Various medicinal plants are used to prevent or cure infectious diseases. The aims of this study were to determine the oil content, fatty acids compositions, and antibacterial activity ofSwietenia macrophylla king seed oil against four multiple-drug-resistant bacteria namely:Staphylococcus aurous, Staphylococcus typhimurium, Pseudomonas aeruginosa andEscherichia coli by disk diffusion method. The lipids were extracted by soxhlet using diethyl ether and n-hexane; and their Free Fatty Acids (FFA) were analyzed by GC-MS. The oil content was 39 to 42.7% and major fatty acid compositions were linoleic (37.50 to 39.21%), oleic (18.82 to 22.03%), stearic (16.75 to 17.65%), and palmitic (14.62 to 15.47%) for diethyl ether and n-hexane, respectively. The antibacterial activity among seed oil was extremely broad and inhibition zones ranged from 0 to 20 mm. These results showed the potential of S. macrophylla seed oil as antimicrobial agent for certain types of bacteria such as S. typhimurium. Moreover, the TLC analysis showed the presence of others constituents such as sterols and this may warrant further research. Academic Journals 2013-07 Article PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/4700/1/Fatty_acid_composition_and_antibacterial_activity_of_Swietenia_Macrophylla_king_seed_oil.pdf M. M., Yusoff and Muhammed, B. Suliman and Nour, A. H. and Azhari, H. Nour and Kuppusamy, Palaniselvam and A. R., Yuvaraj and Adam, Mazza S. (2013) Fatty Acid Composition and Antibacterial Activity of Swietenia Macrophylla King Seed Oil. African Journal of Plant Science, 7 (7). pp. 300-303. ISSN 1996-0824 http://dx.doi.org/10.5897/AJPS2013.1039 DOI: 10.5897/AJPS2013.1039
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	Q Science (General) QD Chemistry
spellingShingle	Q Science (General) QD Chemistry M. M., Yusoff Muhammed, B. Suliman Nour, A. H. Azhari, H. Nour Kuppusamy, Palaniselvam A. R., Yuvaraj Adam, Mazza S. Fatty Acid Composition and Antibacterial Activity of Swietenia Macrophylla King Seed Oil
description	Pathogenic bacteria cause many acute and serious diseases, especially ‘multiple-drug-resistant’ strains have become such a problem due to overuse of antibiotics. Various medicinal plants are used to prevent or cure infectious diseases. The aims of this study were to determine the oil content, fatty acids compositions, and antibacterial activity ofSwietenia macrophylla king seed oil against four multiple-drug-resistant bacteria namely:Staphylococcus aurous, Staphylococcus typhimurium, Pseudomonas aeruginosa andEscherichia coli by disk diffusion method. The lipids were extracted by soxhlet using diethyl ether and n-hexane; and their Free Fatty Acids (FFA) were analyzed by GC-MS. The oil content was 39 to 42.7% and major fatty acid compositions were linoleic (37.50 to 39.21%), oleic (18.82 to 22.03%), stearic (16.75 to 17.65%), and palmitic (14.62 to 15.47%) for diethyl ether and n-hexane, respectively. The antibacterial activity among seed oil was extremely broad and inhibition zones ranged from 0 to 20 mm. These results showed the potential of S. macrophylla seed oil as antimicrobial agent for certain types of bacteria such as S. typhimurium. Moreover, the TLC analysis showed the presence of others constituents such as sterols and this may warrant further research.
format	Article
author	M. M., Yusoff Muhammed, B. Suliman Nour, A. H. Azhari, H. Nour Kuppusamy, Palaniselvam A. R., Yuvaraj Adam, Mazza S.
author_facet	M. M., Yusoff Muhammed, B. Suliman Nour, A. H. Azhari, H. Nour Kuppusamy, Palaniselvam A. R., Yuvaraj Adam, Mazza S.
author_sort	M. M., Yusoff
title	Fatty Acid Composition and Antibacterial Activity of Swietenia Macrophylla King Seed Oil
title_short	Fatty Acid Composition and Antibacterial Activity of Swietenia Macrophylla King Seed Oil
title_full	Fatty Acid Composition and Antibacterial Activity of Swietenia Macrophylla King Seed Oil
title_fullStr	Fatty Acid Composition and Antibacterial Activity of Swietenia Macrophylla King Seed Oil
title_full_unstemmed	Fatty Acid Composition and Antibacterial Activity of Swietenia Macrophylla King Seed Oil
title_sort	fatty acid composition and antibacterial activity of swietenia macrophylla king seed oil
publisher	Academic Journals
publishDate	2013
url	http://umpir.ump.edu.my/id/eprint/4700/ http://umpir.ump.edu.my/id/eprint/4700/ http://umpir.ump.edu.my/id/eprint/4700/ http://umpir.ump.edu.my/id/eprint/4700/1/Fatty_acid_composition_and_antibacterial_activity_of_Swietenia_Macrophylla_king_seed_oil.pdf
first_indexed	2023-09-18T21:59:33Z
last_indexed	2023-09-18T21:59:33Z
_version_	1777414306121383936

Fatty Acid Composition and Antibacterial Activity of Swietenia Macrophylla King Seed Oil

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