Characterization of β-Cyclodextrin Complexes with Natural Dye

Natural dye was successfully solubilised in aqueous solution in forming inclusion complex with β-cyclodextrin (β-CD). To investigate molecular association, phase solubility studies were undertaken. In the presence of cyclodextrin, fluorescence absorbances were enhanced. Solid state inclusion co...

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Bibliographic Details
Main Authors: Mimi Sakinah, A. M., Norasiha, Hamid, Rohaida, Che Man
Format: Conference or Workshop Item
Language:English
Published: 2009
Subjects:
Online Access:http://umpir.ump.edu.my/id/eprint/4146/
http://umpir.ump.edu.my/id/eprint/4146/1/12_NCON-PGR2009.pdf
Description
Summary:Natural dye was successfully solubilised in aqueous solution in forming inclusion complex with β-cyclodextrin (β-CD). To investigate molecular association, phase solubility studies were undertaken. In the presence of cyclodextrin, fluorescence absorbances were enhanced. Solid state inclusion complex was also prepared using co-precipitation method. The solid was characterized using Fourier Transform Infrared (FTIR) and X-ray Diffractometer (XRD). Using FTIR, the host-interaction have been evidenced by monitoring the changes in some guest molecule band relative to those observed in the spectra of the 1:1 physical mixtures and complex. XRD can give the order of structure in the solid inclusion. All the data from FTIR and X-Ray studies showed that it is possible to obtain an inclusion complex (1:1) in solid state.