Optimization of extraction parameters of total phenolic compound from Cosmos caudatus

The wide ranges of extraction parameters used being identified from previous studies derives the need to find the best conditions to yield optimum extraction of total phenolic compounds from Cosmos caudatus. The objective of this research is to determine the optimum extraction parameters, namely ult...

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Main Author:	Hazwani, Zulkiply
Format:	Undergraduates Project Papers
Language:	English
Published:	2012
Subjects:	TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/3600/ http://umpir.ump.edu.my/id/eprint/3600/1/CD6404_HAZWANI_ZULKIPLY.pdf

id	ump-3600
recordtype	eprints
spelling	ump-36002015-03-03T08:02:06Z http://umpir.ump.edu.my/id/eprint/3600/ Optimization of extraction parameters of total phenolic compound from Cosmos caudatus Hazwani, Zulkiply TP Chemical technology The wide ranges of extraction parameters used being identified from previous studies derives the need to find the best conditions to yield optimum extraction of total phenolic compounds from Cosmos caudatus. The objective of this research is to determine the optimum extraction parameters, namely ultrasonic frequency (from 30 to 70 kHz), sample-to-solvent ratio (from 2 to 10 w/v %) and extraction time (from 30 to 300 minutes) of total phenolic compound from Cosmos caudatus. The experimental design was first generated from Response Surface Methodology by using Design Expert 7.1.6 with three independent variables, namely ultrasonic frequency, sample-to-solvent ratio (SSR) and extraction time. Results showed that the optimization of extracting total phenolic compounds (TPC) from Cosmos caudatus can be accomplished by employing ultrasonic frequency of 70 kHz, 2g dry sample/100mL ethanol and extraction time of 300 minutes with yield of 7.7395 mg GAE/g dw which is in close agreement with the predicted value (7.5359 mg GAE/g dw). Analysis of variance showed significant ultrasonic frequency and sample-to-solvent ratio, but insignificant extraction time. This might be partly due to phenolic oxidation during the extraction itself. Since previous and present studies suggests that the extraction of total phenolic compounds can be further optimized, upcoming studies need to be directed at varying the significant extraction parameters including the extraction temperature, types of solvent used and extraction methods. 2012-01 Undergraduates Project Papers NonPeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/3600/1/CD6404_HAZWANI_ZULKIPLY.pdf Hazwani, Zulkiply (2012) Optimization of extraction parameters of total phenolic compound from Cosmos caudatus. Faculty of Chemical Engineering and Natural Resources, Universiti Malaysia Pahang.
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	TP Chemical technology
spellingShingle	TP Chemical technology Hazwani, Zulkiply Optimization of extraction parameters of total phenolic compound from Cosmos caudatus
description	The wide ranges of extraction parameters used being identified from previous studies derives the need to find the best conditions to yield optimum extraction of total phenolic compounds from Cosmos caudatus. The objective of this research is to determine the optimum extraction parameters, namely ultrasonic frequency (from 30 to 70 kHz), sample-to-solvent ratio (from 2 to 10 w/v %) and extraction time (from 30 to 300 minutes) of total phenolic compound from Cosmos caudatus. The experimental design was first generated from Response Surface Methodology by using Design Expert 7.1.6 with three independent variables, namely ultrasonic frequency, sample-to-solvent ratio (SSR) and extraction time. Results showed that the optimization of extracting total phenolic compounds (TPC) from Cosmos caudatus can be accomplished by employing ultrasonic frequency of 70 kHz, 2g dry sample/100mL ethanol and extraction time of 300 minutes with yield of 7.7395 mg GAE/g dw which is in close agreement with the predicted value (7.5359 mg GAE/g dw). Analysis of variance showed significant ultrasonic frequency and sample-to-solvent ratio, but insignificant extraction time. This might be partly due to phenolic oxidation during the extraction itself. Since previous and present studies suggests that the extraction of total phenolic compounds can be further optimized, upcoming studies need to be directed at varying the significant extraction parameters including the extraction temperature, types of solvent used and extraction methods.
format	Undergraduates Project Papers
author	Hazwani, Zulkiply
author_facet	Hazwani, Zulkiply
author_sort	Hazwani, Zulkiply
title	Optimization of extraction parameters of total phenolic compound from Cosmos caudatus
title_short	Optimization of extraction parameters of total phenolic compound from Cosmos caudatus
title_full	Optimization of extraction parameters of total phenolic compound from Cosmos caudatus
title_fullStr	Optimization of extraction parameters of total phenolic compound from Cosmos caudatus
title_full_unstemmed	Optimization of extraction parameters of total phenolic compound from Cosmos caudatus
title_sort	optimization of extraction parameters of total phenolic compound from cosmos caudatus
publishDate	2012
url	http://umpir.ump.edu.my/id/eprint/3600/ http://umpir.ump.edu.my/id/eprint/3600/1/CD6404_HAZWANI_ZULKIPLY.pdf
first_indexed	2023-09-18T21:57:59Z
last_indexed	2023-09-18T21:57:59Z
_version_	1777414207546851328

Optimization of extraction parameters of total phenolic compound from Cosmos caudatus

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