Antibacterial Activity of Different Extracts of Swietenia Macrophylla King

The study was carried out to screen antimicrobial activity for a new natural,nontoxic and effective antibiotic from plant extract. In this study, Swietenia Macrophylla King was selected and antibacterial activity of extracts from different parts (leaf, fruit cover, seed cover) with various...

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Main Authors:	Azhari, H. Nour, Sandanasamy, Jessinta, M. M., Yusoff
Format:	Conference or Workshop Item
Language:	English
Published:	2012
Subjects:	RM Therapeutics. Pharmacology
Online Access:	http://umpir.ump.edu.my/id/eprint/3030/ http://umpir.ump.edu.my/id/eprint/3030/1/MAPS2012%2C_Antibacterial_activity_of_S._macrophylla.pdf

id	ump-3030
recordtype	eprints
spelling	ump-30302018-03-08T06:10:50Z http://umpir.ump.edu.my/id/eprint/3030/ Antibacterial Activity of Different Extracts of Swietenia Macrophylla King Azhari, H. Nour Sandanasamy, Jessinta M. M., Yusoff RM Therapeutics. Pharmacology The study was carried out to screen antimicrobial activity for a new natural,nontoxic and effective antibiotic from plant extract. In this study, Swietenia Macrophylla King was selected and antibacterial activity of extracts from different parts (leaf, fruit cover, seed cover) with various solvents or different fractions of the extracts was studied in laboratory test. The antibacterial activity of these extracts was assessed against two multiple-drug-resistance bacteria strains namely, Escherichia coli and Staphylococcus aureus by the well diffusion method. For the antibacterial bioassay, four concentrations (10, 50, 100 and 150 µg mL-1 ) of each extract solutions were prepared. The antibacterial activity among extracts was extremely broad against both test organisms. Minimum inhibition concentration was done serial dilution method. The MIC values of the extracts ranged from 8.1 to 21.2 µg mL-1 . Among fractionated extracts, fraction 4 (F4) of fruit cover more potent than other fractions, whereas among solvent crude extracts; the ethanol extracts from fruit cover (EFC) displayed overall more potent activity than other parts against both tested bacteria. The experimental results obtained from this study suggest that Swietenia Macrophylla King is promising as natural antibacterial. Some bioactive groups were screened by TLC; and the results obtained were positive and this may warrant further research to determine the bioactive compound(s). 2012 Conference or Workshop Item PeerReviewed application/pdf en http://umpir.ump.edu.my/id/eprint/3030/1/MAPS2012%2C_Antibacterial_activity_of_S._macrophylla.pdf Azhari, H. Nour and Sandanasamy, Jessinta and M. M., Yusoff (2012) Antibacterial Activity of Different Extracts of Swietenia Macrophylla King. In: 13th Medicinal and Aromatic Plants Seminar 2012 (MAPS2012), 25-26 September 2012 , Hotel Sunway Putra, Kuala Lumpur. .
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	RM Therapeutics. Pharmacology
spellingShingle	RM Therapeutics. Pharmacology Azhari, H. Nour Sandanasamy, Jessinta M. M., Yusoff Antibacterial Activity of Different Extracts of Swietenia Macrophylla King
description	The study was carried out to screen antimicrobial activity for a new natural,nontoxic and effective antibiotic from plant extract. In this study, Swietenia Macrophylla King was selected and antibacterial activity of extracts from different parts (leaf, fruit cover, seed cover) with various solvents or different fractions of the extracts was studied in laboratory test. The antibacterial activity of these extracts was assessed against two multiple-drug-resistance bacteria strains namely, Escherichia coli and Staphylococcus aureus by the well diffusion method. For the antibacterial bioassay, four concentrations (10, 50, 100 and 150 µg mL-1 ) of each extract solutions were prepared. The antibacterial activity among extracts was extremely broad against both test organisms. Minimum inhibition concentration was done serial dilution method. The MIC values of the extracts ranged from 8.1 to 21.2 µg mL-1 . Among fractionated extracts, fraction 4 (F4) of fruit cover more potent than other fractions, whereas among solvent crude extracts; the ethanol extracts from fruit cover (EFC) displayed overall more potent activity than other parts against both tested bacteria. The experimental results obtained from this study suggest that Swietenia Macrophylla King is promising as natural antibacterial. Some bioactive groups were screened by TLC; and the results obtained were positive and this may warrant further research to determine the bioactive compound(s).
format	Conference or Workshop Item
author	Azhari, H. Nour Sandanasamy, Jessinta M. M., Yusoff
author_facet	Azhari, H. Nour Sandanasamy, Jessinta M. M., Yusoff
author_sort	Azhari, H. Nour
title	Antibacterial Activity of Different Extracts of Swietenia Macrophylla King
title_short	Antibacterial Activity of Different Extracts of Swietenia Macrophylla King
title_full	Antibacterial Activity of Different Extracts of Swietenia Macrophylla King
title_fullStr	Antibacterial Activity of Different Extracts of Swietenia Macrophylla King
title_full_unstemmed	Antibacterial Activity of Different Extracts of Swietenia Macrophylla King
title_sort	antibacterial activity of different extracts of swietenia macrophylla king
publishDate	2012
url	http://umpir.ump.edu.my/id/eprint/3030/ http://umpir.ump.edu.my/id/eprint/3030/1/MAPS2012%2C_Antibacterial_activity_of_S._macrophylla.pdf
first_indexed	2023-09-18T21:57:03Z
last_indexed	2023-09-18T21:57:03Z
_version_	1777414148880072704

Antibacterial Activity of Different Extracts of Swietenia Macrophylla King

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