Development of biomimetic electrospun polymeric biomaterials for bone tissue engineering. A review

Electrospinning is a promising and versatile technique that is used to fabricate polymeric nanofibrous scaffolds for bone tissue engineering. Ideal scaffolds should be biocompatible and bioactive with appropriate surface chemistry, good mechanical properties and should mimic the natural extracellula...

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Main Authors:	Chahal, Sugandha, Kumar, A, Jahir Hussain, Fathima Shahitha
Format:	Article
Language:	English
Published:	Taylor and Francis Inc. 2019
Subjects:	QD Chemistry QH Natural history R Medicine (General) TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/26500/ http://umpir.ump.edu.my/id/eprint/26500/ http://umpir.ump.edu.my/id/eprint/26500/ http://umpir.ump.edu.my/id/eprint/26500/1/Development%20of%20biomimetic%20electrospun%20polymeric%20biomaterials%20for%20bone%20.pdf

id	ump-26500
recordtype	eprints
spelling	ump-265002019-12-09T07:41:17Z http://umpir.ump.edu.my/id/eprint/26500/ Development of biomimetic electrospun polymeric biomaterials for bone tissue engineering. A review Chahal, Sugandha Kumar, A Jahir Hussain, Fathima Shahitha QD Chemistry QH Natural history R Medicine (General) TP Chemical technology Electrospinning is a promising and versatile technique that is used to fabricate polymeric nanofibrous scaffolds for bone tissue engineering. Ideal scaffolds should be biocompatible and bioactive with appropriate surface chemistry, good mechanical properties and should mimic the natural extracellular matrix (ECM) of bone. Selection of the most appropriate material to produce a scaffold is an important step towards the construction of a tissue engineered product. Bone tissue engineering is an interdisciplinary field, where the principles of engineering are applied on bone-related biochemical reactions. Scaffolds, cells, growth factors, and their interrelation in microenvironment are the major concerns in bone tissue engineering. This review covers the latest development of biomimetic electrospun polymeric biomaterials for bone tissue engineering. It includes the brief details to bone tissue engineering along with bone structure and ideal bone scaffolds requirements. Details about various engineered materials and methodologies used for bone scaffolds development were discussed. Description of electrospinning technique and its parameters relating their fabrication, advantages, and applications in bone tissue engineering were also presented. The use of synthetic and natural polymers based electrospun nanofibrous scaffolds for bone tissue engineering and their biomineralization processes were discussed and reviewed comprehensively. Finally, we give conclusion along with perspectives and challenges of biomimetic scaffolds for bone tissue engineering based on electrospun nanofibers. Taylor and Francis Inc. 2019-09-22 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/26500/1/Development%20of%20biomimetic%20electrospun%20polymeric%20biomaterials%20for%20bone%20.pdf Chahal, Sugandha and Kumar, A and Jahir Hussain, Fathima Shahitha (2019) Development of biomimetic electrospun polymeric biomaterials for bone tissue engineering. A review. Journal of Biomaterials Science, Polymer Edition, 30 (14). pp. 1308-1355. ISSN 0920-5063 https://doi.org/10.1080/09205063.2019.1630699 https://doi.org/10.1080/09205063.2019.1630699
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	QD Chemistry QH Natural history R Medicine (General) TP Chemical technology
spellingShingle	QD Chemistry QH Natural history R Medicine (General) TP Chemical technology Chahal, Sugandha Kumar, A Jahir Hussain, Fathima Shahitha Development of biomimetic electrospun polymeric biomaterials for bone tissue engineering. A review
description	Electrospinning is a promising and versatile technique that is used to fabricate polymeric nanofibrous scaffolds for bone tissue engineering. Ideal scaffolds should be biocompatible and bioactive with appropriate surface chemistry, good mechanical properties and should mimic the natural extracellular matrix (ECM) of bone. Selection of the most appropriate material to produce a scaffold is an important step towards the construction of a tissue engineered product. Bone tissue engineering is an interdisciplinary field, where the principles of engineering are applied on bone-related biochemical reactions. Scaffolds, cells, growth factors, and their interrelation in microenvironment are the major concerns in bone tissue engineering. This review covers the latest development of biomimetic electrospun polymeric biomaterials for bone tissue engineering. It includes the brief details to bone tissue engineering along with bone structure and ideal bone scaffolds requirements. Details about various engineered materials and methodologies used for bone scaffolds development were discussed. Description of electrospinning technique and its parameters relating their fabrication, advantages, and applications in bone tissue engineering were also presented. The use of synthetic and natural polymers based electrospun nanofibrous scaffolds for bone tissue engineering and their biomineralization processes were discussed and reviewed comprehensively. Finally, we give conclusion along with perspectives and challenges of biomimetic scaffolds for bone tissue engineering based on electrospun nanofibers.
format	Article
author	Chahal, Sugandha Kumar, A Jahir Hussain, Fathima Shahitha
author_facet	Chahal, Sugandha Kumar, A Jahir Hussain, Fathima Shahitha
author_sort	Chahal, Sugandha
title	Development of biomimetic electrospun polymeric biomaterials for bone tissue engineering. A review
title_short	Development of biomimetic electrospun polymeric biomaterials for bone tissue engineering. A review
title_full	Development of biomimetic electrospun polymeric biomaterials for bone tissue engineering. A review
title_fullStr	Development of biomimetic electrospun polymeric biomaterials for bone tissue engineering. A review
title_full_unstemmed	Development of biomimetic electrospun polymeric biomaterials for bone tissue engineering. A review
title_sort	development of biomimetic electrospun polymeric biomaterials for bone tissue engineering. a review
publisher	Taylor and Francis Inc.
publishDate	2019
url	http://umpir.ump.edu.my/id/eprint/26500/ http://umpir.ump.edu.my/id/eprint/26500/ http://umpir.ump.edu.my/id/eprint/26500/ http://umpir.ump.edu.my/id/eprint/26500/1/Development%20of%20biomimetic%20electrospun%20polymeric%20biomaterials%20for%20bone%20.pdf
first_indexed	2023-09-18T22:41:19Z
last_indexed	2023-09-18T22:41:19Z
_version_	1777416933749030912

Development of biomimetic electrospun polymeric biomaterials for bone tissue engineering. A review

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