Determination of favorable blood glucose target range for stochastic TARgeted (STAR) glycemic control in Malaysia

Stress-induced hyperglycemia is common in critically ill patients, but there is uncertainty about what constitutes an optimal blood glucose target range for glycemic control. Furthermore, to reduce the rate of hyperglycemic and hypoglycemic events, model-based glycemic control protocols have been in...

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Main Authors:	Abu-Samah, Asma, Normy Norfiza, Abdul Razak, Ummu Kulthum, Jamaludin, Fatanah, M. Suhaimi, Azrina, M. Ralib
Format:	Article
Language:	English
Published:	Institute of Advanced Engineering and Science 2019
Subjects:	R Medicine (General) RC Internal medicine TS Manufactures
Online Access:	http://umpir.ump.edu.my/id/eprint/25225/ http://umpir.ump.edu.my/id/eprint/25225/ http://umpir.ump.edu.my/id/eprint/25225/ http://umpir.ump.edu.my/id/eprint/25225/1/Determination%20of%20favorable%20blood%20glucose%20target%20range.pdf

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spelling	ump-252252019-10-24T08:41:12Z http://umpir.ump.edu.my/id/eprint/25225/ Determination of favorable blood glucose target range for stochastic TARgeted (STAR) glycemic control in Malaysia Abu-Samah, Asma Normy Norfiza, Abdul Razak Ummu Kulthum, Jamaludin Fatanah, M. Suhaimi Azrina, M. Ralib R Medicine (General) RC Internal medicine TS Manufactures Stress-induced hyperglycemia is common in critically ill patients, but there is uncertainty about what constitutes an optimal blood glucose target range for glycemic control. Furthermore, to reduce the rate of hyperglycemic and hypoglycemic events, model-based glycemic control protocols have been introduced, such as the stochastic targeted (STAR) glycemic control protocol. This protocol has been used in the intensive care units of Christchurch and Gyulà Hospital since 2010, and in Malaysia since 2017. In this study, we analyzed the adaptability of the protocol and identified the blood glucose target range most favorable for use in the Malaysian population. Virtual simulation results are presented for two clinical cohorts: one receiving treatment by the STAR protocol itself and the other receiving intensive insulin therapy by the sliding scale method. Performance and safety were analyzed using five clinical target ranges, and best control was simulated at a target range of 6.0–10.0 mmol/L. This target range had the best balance of performance, with the lowest risk of hypoglycemia and the lowest requirement for nursing interventions. The result is encouraging as the STAR protocol is suitable to provide better and safer glycemic control while using a target range that is already widely used in Malaysian intensive care units Institute of Advanced Engineering and Science 2019-07 Article PeerReviewed pdf en cc_by_nc_4 http://umpir.ump.edu.my/id/eprint/25225/1/Determination%20of%20favorable%20blood%20glucose%20target%20range.pdf Abu-Samah, Asma and Normy Norfiza, Abdul Razak and Ummu Kulthum, Jamaludin and Fatanah, M. Suhaimi and Azrina, M. Ralib (2019) Determination of favorable blood glucose target range for stochastic TARgeted (STAR) glycemic control in Malaysia. Indonesian Journal of Electrical Engineering and Computer Science, 15 (1). pp. 133-141. ISSN 2502-4752 http://doi.org/10.11591/ijeecs.v15.i1.pp133-141 http://doi.org/10.11591/ijeecs.v15.i1.pp133-141
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	R Medicine (General) RC Internal medicine TS Manufactures
spellingShingle	R Medicine (General) RC Internal medicine TS Manufactures Abu-Samah, Asma Normy Norfiza, Abdul Razak Ummu Kulthum, Jamaludin Fatanah, M. Suhaimi Azrina, M. Ralib Determination of favorable blood glucose target range for stochastic TARgeted (STAR) glycemic control in Malaysia
description	Stress-induced hyperglycemia is common in critically ill patients, but there is uncertainty about what constitutes an optimal blood glucose target range for glycemic control. Furthermore, to reduce the rate of hyperglycemic and hypoglycemic events, model-based glycemic control protocols have been introduced, such as the stochastic targeted (STAR) glycemic control protocol. This protocol has been used in the intensive care units of Christchurch and Gyulà Hospital since 2010, and in Malaysia since 2017. In this study, we analyzed the adaptability of the protocol and identified the blood glucose target range most favorable for use in the Malaysian population. Virtual simulation results are presented for two clinical cohorts: one receiving treatment by the STAR protocol itself and the other receiving intensive insulin therapy by the sliding scale method. Performance and safety were analyzed using five clinical target ranges, and best control was simulated at a target range of 6.0–10.0 mmol/L. This target range had the best balance of performance, with the lowest risk of hypoglycemia and the lowest requirement for nursing interventions. The result is encouraging as the STAR protocol is suitable to provide better and safer glycemic control while using a target range that is already widely used in Malaysian intensive care units
format	Article
author	Abu-Samah, Asma Normy Norfiza, Abdul Razak Ummu Kulthum, Jamaludin Fatanah, M. Suhaimi Azrina, M. Ralib
author_facet	Abu-Samah, Asma Normy Norfiza, Abdul Razak Ummu Kulthum, Jamaludin Fatanah, M. Suhaimi Azrina, M. Ralib
author_sort	Abu-Samah, Asma
title	Determination of favorable blood glucose target range for stochastic TARgeted (STAR) glycemic control in Malaysia
title_short	Determination of favorable blood glucose target range for stochastic TARgeted (STAR) glycemic control in Malaysia
title_full	Determination of favorable blood glucose target range for stochastic TARgeted (STAR) glycemic control in Malaysia
title_fullStr	Determination of favorable blood glucose target range for stochastic TARgeted (STAR) glycemic control in Malaysia
title_full_unstemmed	Determination of favorable blood glucose target range for stochastic TARgeted (STAR) glycemic control in Malaysia
title_sort	determination of favorable blood glucose target range for stochastic targeted (star) glycemic control in malaysia
publisher	Institute of Advanced Engineering and Science
publishDate	2019
url	http://umpir.ump.edu.my/id/eprint/25225/ http://umpir.ump.edu.my/id/eprint/25225/ http://umpir.ump.edu.my/id/eprint/25225/ http://umpir.ump.edu.my/id/eprint/25225/1/Determination%20of%20favorable%20blood%20glucose%20target%20range.pdf
first_indexed	2023-09-18T22:38:37Z
last_indexed	2023-09-18T22:38:37Z
_version_	1777416764199534592

Determination of favorable blood glucose target range for stochastic TARgeted (STAR) glycemic control in Malaysia

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