The effect of ZnO nanoparticles on the physical, mechanical, and antibacterial properties of chitosan/gelatin hydrogel films

Apart from biocompatibility, hydrogel films with good physical, morphology, swelling, and antibacterial properties are required for biomedical applications. In this study, the effects of nanofiller (i.e., zinc oxide (ZnO) nanoparticles) on physical, morphology, swelling, and antibacterial properties...

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Main Authors:	Nurul Amira, Ahmad Yusof, Norashikin, Mat Zain
Format:	Article
Language:	English
Published:	Penerbit Universiti Teknologi Malaysia 2019
Subjects:	QD Chemistry TP Chemical technology
Online Access:	http://umpir.ump.edu.my/id/eprint/24833/ http://umpir.ump.edu.my/id/eprint/24833/ http://umpir.ump.edu.my/id/eprint/24833/ http://umpir.ump.edu.my/id/eprint/24833/1/The%20effect%20of%20ZnO%20nanoparticles%20on%20the%20physical.pdf

id	ump-24833
recordtype	eprints
spelling	ump-248332019-04-30T03:31:46Z http://umpir.ump.edu.my/id/eprint/24833/ The effect of ZnO nanoparticles on the physical, mechanical, and antibacterial properties of chitosan/gelatin hydrogel films Nurul Amira, Ahmad Yusof Norashikin, Mat Zain QD Chemistry TP Chemical technology Apart from biocompatibility, hydrogel films with good physical, morphology, swelling, and antibacterial properties are required for biomedical applications. In this study, the effects of nanofiller (i.e., zinc oxide (ZnO) nanoparticles) on physical, morphology, swelling, and antibacterial properties of hydrogel film were investigated. The new chitosan/gelatin/ZnO hydrogel films were synthesized using solution casting method by blending the chitosan and gelatin solutions with ZnO nanoparticles. The use of glycerol (plasticizing agent) could enhance the durability and flexibility of the hydrogel film. From the FTIR results, it was found that chemical reactions occurred of gelatin was between 1500 cm-1 to 800 cm-1. On the other hand, the SEM results showed that the pore size distribution within the hydrogel film varied from 20µm to 700µm. The antibacterial properties ZnO hydrogel film against bacteria such as Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) were evaluated using the zone of inhibition method. The antibacterial activity (against the S. aureus bacteria) of the new ZnO hydrogel film was more promising than that of the nanoparticle-free hydrogel film. The current findings showed that the new chitosan/gelatin/ZnO hydrogel film could be used in biomedical application. Penerbit Universiti Teknologi Malaysia 2019-03 Article PeerReviewed pdf en http://umpir.ump.edu.my/id/eprint/24833/1/The%20effect%20of%20ZnO%20nanoparticles%20on%20the%20physical.pdf Nurul Amira, Ahmad Yusof and Norashikin, Mat Zain (2019) The effect of ZnO nanoparticles on the physical, mechanical, and antibacterial properties of chitosan/gelatin hydrogel films. Jurnal Teknologi (Sciences and Engineering), 81 (2). pp. 21-26. ISSN 0127-9696 (print); 2180-3722 (online) https://doi.org/10.11113/jt.v81.12605 https://doi.org/10.11113/jt.v81.12605
repository_type	Digital Repository
institution_category	Local University
institution	Universiti Malaysia Pahang
building	UMP Institutional Repository
collection	Online Access
language	English
topic	QD Chemistry TP Chemical technology
spellingShingle	QD Chemistry TP Chemical technology Nurul Amira, Ahmad Yusof Norashikin, Mat Zain The effect of ZnO nanoparticles on the physical, mechanical, and antibacterial properties of chitosan/gelatin hydrogel films
description	Apart from biocompatibility, hydrogel films with good physical, morphology, swelling, and antibacterial properties are required for biomedical applications. In this study, the effects of nanofiller (i.e., zinc oxide (ZnO) nanoparticles) on physical, morphology, swelling, and antibacterial properties of hydrogel film were investigated. The new chitosan/gelatin/ZnO hydrogel films were synthesized using solution casting method by blending the chitosan and gelatin solutions with ZnO nanoparticles. The use of glycerol (plasticizing agent) could enhance the durability and flexibility of the hydrogel film. From the FTIR results, it was found that chemical reactions occurred of gelatin was between 1500 cm-1 to 800 cm-1. On the other hand, the SEM results showed that the pore size distribution within the hydrogel film varied from 20µm to 700µm. The antibacterial properties ZnO hydrogel film against bacteria such as Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) were evaluated using the zone of inhibition method. The antibacterial activity (against the S. aureus bacteria) of the new ZnO hydrogel film was more promising than that of the nanoparticle-free hydrogel film. The current findings showed that the new chitosan/gelatin/ZnO hydrogel film could be used in biomedical application.
format	Article
author	Nurul Amira, Ahmad Yusof Norashikin, Mat Zain
author_facet	Nurul Amira, Ahmad Yusof Norashikin, Mat Zain
author_sort	Nurul Amira, Ahmad Yusof
title	The effect of ZnO nanoparticles on the physical, mechanical, and antibacterial properties of chitosan/gelatin hydrogel films
title_short	The effect of ZnO nanoparticles on the physical, mechanical, and antibacterial properties of chitosan/gelatin hydrogel films
title_full	The effect of ZnO nanoparticles on the physical, mechanical, and antibacterial properties of chitosan/gelatin hydrogel films
title_fullStr	The effect of ZnO nanoparticles on the physical, mechanical, and antibacterial properties of chitosan/gelatin hydrogel films
title_full_unstemmed	The effect of ZnO nanoparticles on the physical, mechanical, and antibacterial properties of chitosan/gelatin hydrogel films
title_sort	effect of zno nanoparticles on the physical, mechanical, and antibacterial properties of chitosan/gelatin hydrogel films
publisher	Penerbit Universiti Teknologi Malaysia
publishDate	2019
url	http://umpir.ump.edu.my/id/eprint/24833/ http://umpir.ump.edu.my/id/eprint/24833/ http://umpir.ump.edu.my/id/eprint/24833/ http://umpir.ump.edu.my/id/eprint/24833/1/The%20effect%20of%20ZnO%20nanoparticles%20on%20the%20physical.pdf
first_indexed	2023-09-18T22:37:49Z
last_indexed	2023-09-18T22:37:49Z
_version_	1777416714125836288

The effect of ZnO nanoparticles on the physical, mechanical, and antibacterial properties of chitosan/gelatin hydrogel films

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